791643C

18:1-d7 Lyso PC

Avanti Research^™ - A Croda Brand

• Sinonimo/i: 1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphocholine
• Formula empirica (notazione di Hill): C₂₆H₄₅D₇NO₇P
• Numero CAS: 2097561-13-0
• Peso molecolare: 528.71
• Codice UNSPSC: 41141825
• NACRES: NA.25

Proprietà

• Saggio: >99% (TLC)
• Forma fisica: liquid
• Confezionamento: pkg of 1 × 1 mL (791643C-1mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand
• Concentrazione: 1 mg/mL (791643C-1mg)
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

18:1-d7 Lyso PC 1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphocholine is a deuterated phospholipid. The lipid lysophosphatidylcholine is esterified with oleic acid. Oleic acid harbors the deuterium ions. Lysophosphatidylcholine (LPC) is derived from phosphatidylcholine by the action of enzyme phospholipase A2.

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH^™ LIPIDOMIX^™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Applicazioni

18:1-d7 Lyso PC has been used:

• as an internal standard in high performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESIMS/MS) for the lipidomics analysis of bone marrow-derived macrophages
• as a component of extraction solvent for lipid isolation from biological samples
• as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)

Azioni biochim/fisiol

Lysophosphatidylcholine (LPC). Elevated levels of LPC is associated with diabetes and cardiovascular diseases. LPC stimulates cytokines and is implicated in allergic disease. It also elicits lysis on membranes.

Confezionamento

5 mL Clear Glass Sealed Ampule (791643C-1mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

SPLASH is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Consigli di prudenza: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organi bersaglio: Central nervous system, Liver,Kidney
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): does not flash
• Punto d’infiammabilità (°C): does not flash