907383

Fmoc-L-Photo-Lysine

≥95%

• Sinonimo/i: N²-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N⁶-[[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine
• Formula empirica (notazione di Hill): C₂₆H₃₀N₄O₆
• Numero CAS: 2250437-42-2
• Peso molecolare: 494.54
• Codice UNSPSC: 12352209

Proprietà

• Saggio: ≥95%
• Stato: solid
• Impiego in reazioni chimiche: reaction type: Fmoc solid-phase peptide synthesis
• applicazioni: peptide synthesis
• Gruppo funzionale: Fmoc
• Temperatura di conservazione: 2-8°C

Descrizione

Applicazioni

Fmoc-L-Photo-Lysine is a diazirine-containing, Fmoc-protected lysine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907251.

Altre note

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable