177466
4-Methylcyclohexylamine, mixture of cis and trans
97%
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About This Item
Prodotti consigliati
Saggio
97%
Forma fisica
liquid
Indice di rifrazione
n20/D 1.4531 (lit.)
P. eboll.
151-154 °C (lit.)
Densità
0.855 g/mL at 25 °C (lit.)
Stringa SMILE
CC1CCC(N)CC1
InChI
1S/C7H15N/c1-6-2-4-7(8)5-3-6/h6-7H,2-5,8H2,1H3
KSMVBYPXNKCPAJ-UHFFFAOYSA-N
Descrizione generale
Trans-4-methylcyclohexylamine is a spermidine synthase inhibitor.
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Flam. Liq. 3 - Skin Corr. 1B
Codice della classe di stoccaggio
3 - Flammable liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
80.6 °F - closed cup
Punto d’infiammabilità (°C)
27 °C - closed cup
Dispositivi di protezione individuale
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 845(1), 80-83 (2006-08-26)
An assay for spermidine synthase (SPDS) activity in rat liver has been developed using micellar electrokinetic chromatography (MEKC) with laser-induced fluorescence (LIF) detection to enable the discovery of SPDS inhibitors. The assay was established by estimating the amount of spermidine
Trans-4-methylcyclohexylamine, a potent new inhibitor of spermidine synthase.
Chemical & pharmaceutical bulletin, 36(8), 3220-3222 (1988-08-01)
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 126(8), 529-542 (2006-08-02)
This review describes my work in the field of polyamine research for the last 35 years. My research started with developing the improved synthesis of decarboxylated S-adenosylmethionine and then moved to the purification of spermidine synthase from rat prostate. I
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Biological & pharmaceutical bulletin, 28(4), 569-573 (2005-04-02)
In rat tissues, a decrease in spermidine, accompanied by an increase in spermine was induced by the oral administration (once daily for either 1 week or 1 month) of trans-4-methylcyclohexylamine (4MCHA), a spermidine synthase inhibitor. This is similar to the
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