1370280

Loratadine Related Compound A

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): Desloratadine, 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine, Clarinex^®, NSC 675447
• Fórmula empírica (Notação de Hill): C₁₉H₁₉ClN₂
• Número CAS: 100643-71-8
• Peso molecular: 310.82
• Número MDL: MFCD00871949
• Código UNSPSC: 41116107
• ID de substância PubChem: 329750257
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: loratadine
• fabricante/nome comercial: USP
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• cadeia de caracteres SMILES: Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1
• InChI: 1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
• chave InChI: JAUOIFJMECXRGI-UHFFFAOYSA-N
• Informações sobre genes: human ... HRH1(3269)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Loratadine Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Loratadine Orally Disintegrating Tablets
• Loratadine Chewable Tablets
• Loratadine Capsules

Ações bioquímicas/fisiológicas

Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações legais

Clarinex is a registered trademark of Schering Corp.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 390.2 °F - Pensky-Martens closed cup
• Ponto de fulgor (°C): 199 °C - Pensky-Martens closed cup