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1287030

USP

Furosemide Related Compound B

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

4-Chloro-5-sulfamoylanthranilic acid

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About This Item

Fórmula empírica (Notação de Hill):
C7H7ClN2O4S
Número CAS:
3086-91-7
Peso molecular:
250.66
Número MDL:
MFCD03423689
Código UNSPSC:
41116107
ID de substância PubChem:
329749918
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

furosemide

fabricante/nome comercial

USP

pf

267 °C (dec.) (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

cadeia de caracteres SMILES

Nc1cc(Cl)c(cc1C(O)=O)S(N)(=O)=O

InChI

1S/C7H7ClN2O4S/c8-4-2-5(9)3(7(11)12)1-6(4)15(10,13)14/h1-2H,9H2,(H,11,12)(H2,10,13,14)

chave InChI

QQLJBZFXGDHSRU-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Furosemide Related Compound B USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

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Pictogramas

Environment
GHS09

Frases de perigo

H411

Declarações de precaução

P273

Classificações de perigo

Aquatic Chronic 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Lot/Batch Number

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Furosemide Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1057

Furosemide

[Determination of furosemide and its metabolic products in plasma and urine by high performance liquid chromatography and clinical application].
Y Miwa et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 108(11), 1087-1092 (1988-11-01)
D E Smith et al.
Drug metabolism and disposition: the biological fate of chemicals, 8(5), 337-342 (1980-09-01)
The objectives of this study were to qualitatively and quantitatively compare the metabolism, pharmacokinetics, and bioavailability of furosemide in healthy volunteers after intravenous and oral administration. We also determined the plasma protein binding of furosemide in vivo after iv administration.
G M Hanna et al.
Journal of AOAC International, 76(3), 526-530 (1993-05-01)
A simple, specific, and accurate proton nuclear magnetic resonance (1H-NMR) spectroscopic method has been developed for the identification and assay of furosemide and its degradation product, 4-chloro-5-sulfamoylanthranilic acid (CSA), in tablets and injections. Dissolution of the sample in D2O-NaOD resulted
H Nakahama et al.
European journal of clinical pharmacology, 32(3), 313-315 (1987-01-01)
Urine from 5 renal transplant recipients treated with frusemide was analyzed for unchanged frusemide (F), glucuronidated frusemide (G) and 4-chloro-5-sulfamoylanthranilic acid (CSA) by HPLC. In 3 recipients, whose renal function recovered steadily and whose hepatic function was normal throughout, the
L Z Benet et al.
Federation proceedings, 42(6), 1695-1698 (1983-04-01)
A variety of furosemide assays and their application to biological samples have been described over the past 2 decades. We describe development of a specific, sensitive assay appropriate for efficient measurement of large numbers of biological samples. With development of
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