1065210

Berberine chloride

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): Berberine chloride form, Natural Yellow 18
• Fórmula empírica (Notação de Hill): C₂₀H₁₈ClNO₄
• Número CAS: 633-65-8
• Peso molecular: 371.81
• Número do índice de cores: 75160
• Beilstein: 3836585
• Número MDL: MFCD00011939
• Código UNSPSC: 41116107
• ID de substância PubChem: 329748923
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: berberine
• fabricante/nome comercial: USP
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• cadeia de caracteres SMILES: COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
• InChI: 1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
• chave InChI: VKJGBAJNNALVAV-UHFFFAOYSA-M

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Berberine chloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Coptis Species Rhizome
• Coptis Species Rhizome Dry Extract
• Coptis Species Rhizome Powder
• Goldenseal
• Indian Barberry Stem
• Indian Barberry Stem Dry Extract
• Indian Barberry Stem Powder

Fluorescent stain for heparin in mast cells

Ações bioquímicas/fisiológicas

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable