BP1108

Berberine chloride

British Pharmacopoeia (BP) Reference Standard

• Sinônimo(s): Berberine chloride form, Natural Yellow 18
• Fórmula empírica (Notação de Hill): C₂₀H₁₈ClNO₄
• Número CAS: 633-65-8
• Peso molecular: 371.81
• Número do índice de cores: 75160
• Beilstein: 3836585
• Número MDL: MFCD00011939
• Código UNSPSC: 12352210
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: berberine
• Formulário: solid
• prazo de validade: limited shelf life, expiry date on the label
• fabricante/nome comercial: BP
• aplicação(ões): pharmaceutical; pharmaceutical small molecule
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
• InChI: 1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
• chave InChI: VKJGBAJNNALVAV-UHFFFAOYSA-M

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Berberine chloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Phellodendron Chinense Bark

Phellodendron Amurense Bark

Fluorescent stain for heparin in mast cells

Ações bioquímicas/fisiológicas

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

Embalagem

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Outras notas

Sales restrictions may apply.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable