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47773

Supelco

Phylloquinone (K1)

analytical standard

Sinônimo(s):

Vitamin K1, 2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, Vitamin K1(20)

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About This Item

Fórmula empírica (Notação de Hill):
C31H46O2
Número CAS:
84-80-0
Peso molecular:
450.70
Beilstein:
2568816
Número CE:
201-564-2
Número MDL:
MFCD00214063
Código UNSPSC:
12164500
ID de substância PubChem:
24871410

grau

analytical standard

Nível de qualidade

100

Formulário

oil

Certificado de análise (CofA)

current certificate can be downloaded

Características

standard type fat soluble vitamin

embalagem

ampule of 100 mg

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

índice de refração

n20/D 1.527 (lit.)

pf

−20 °C (lit.)

densidade

0.984 g/mL at 25 °C (lit.)

aplicação(ões)

food and beverages

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O

InChI

1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1

chave InChI

MBWXNTAXLNYFJB-NKFFZRIASA-N

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Categorias relacionadas

Descrição geral

Phylloquinone (K1) is a prenylated naphthoquinone. It is a fat soluble vitamin, produced by plants, green algae and some species of cyanobacteria. It functions as a coenzyme and is important for the synthesis of a number of proteins involved in blood clotting and bone metabolism.

Aplicação

Phylloquinone (K1) may be used as an analytical reference standard for the quantification of the analyte in olive oil, chard, human plasma samples, animal and plant food products using reversed-phase high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
LC26460V
LC25933V
LC25066V
LC24448V
LC24447V

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Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

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Phytomenadione European Pharmacopoeia (EP) Reference Standard

P1609000

Phytomenadione

Vitamin K1-4a,5,6,7,8,8a-13C6 ≥99 atom % 13C, ≥98% (CP)

Sigma-Aldrich

809888

Vitamin K1-4a,5,6,7,8,8a-13C6

Menadione (K3) analytical standard

Supelco

47775

Menadione (K3)

Vitamin K1 2,3-epoxide ≥98.0% (HPLC)

Sigma-Aldrich

19697

Vitamin K1 2,3-epoxide

(±)-α-Tocoferol analytical standard

Supelco

47783

(±)-α-Tocoferol

Piridoxina analytical standard

Supelco

47862

Piridoxina

Vitamin K2 (MK-4) solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

V-031

Vitamin K2 (MK-4) solution

Colecalciferol (D3) analytical standard

Supelco

47763

Colecalciferol (D3)

Determination of vitamin K1 content in olive oil, chard and human plasma by RP-HPLC method with UV?Vis detection
Otles S and Cagindi O
Food Chemistry, 100(3), 1220-1222 (2007)
Application of a simplified HPLC assay for the determination of phylloquinone (vitamin K1) in animal and plant food items
Jakob E and Elmadfa I
Food Chemistry, 56(1), 87-91 (1996)
Rogier Caluwé et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 29(7), 1385-1390 (2013-11-29)
Haemodialysis patients suffer from accelerated vascular calcification. The vitamin K-dependent matrix Gla protein (MGP) is one of the most powerful inhibitors of vascular calcification. Haemodialysis patients have high levels of the inactive form of MGP (desphosphorylated-uncarboxylated-MGP, dp-uc-MGP) and may benefit
Thilo Krüger et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(11), 2618-2624 (2013-08-31)
Vascular calcification is an independent risk factor for cardiovascular disease. Once thought to be a passive process, vascular calcification is now known to be actively prevented by proteins acting systemically (fetuin-A) or locally (matrix Gla protein). Warfarin is a vitamin
Joline W J Beulens et al.
The British journal of nutrition, 110(8), 1357-1368 (2013-04-18)
Recent reports have attributed the potential health benefits of vitamin K beyond its function to activate hepatic coagulation factors. Moreover, several studies have suggested that menaquinones, also known as vitamin K2, may be more effective in activating extra-hepatic vitamin K-dependent
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Protocolos

HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase

Separation of Retinyl acetate, analytical standard; δ-Tocopherol, analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Retinol palmitate, analytical standard.

HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase

Separation of Retinyl acetate, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; δ-Tocopherol, analytical standard; Retinol palmitate, analytical standard

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