PHR1078

Phytonadione

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): Vitamin K₁, Phytomenadione, 2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, Vitamin K₁₍₂₀₎
• Fórmula empírica (Notação de Hill): C₃₁H₄₆O₂
• Número CAS: 84-80-0
• Peso molecular: 450.70
• Beilstein: 2568816
• Número CE: 201-564-2
• Número MDL: MFCD00214063
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823101
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to BP 423; traceable to Ph. Eur. P1609000; traceable to USP 1538006
• família API: phytonadione
• Certificado de análise (CofA): current certificate can be downloaded
• condição de armazenamento: protect from light
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• índice de refração: n20/D 1.527 (lit.)
• pf: −20 °C (lit.)
• densidade: 0.984 g/mL at 25 °C (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O
• InChI: 1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
• chave InChI: MBWXNTAXLNYFJB-NKFFZRIASA-N

Descrição

Descrição geral

Phytonadione belongs to the category of oral anticonvulsant drugs. It protects a newborn from acquiring hemorrhagic diseases by maintaining a normal blood clotting mechanism.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Phytonadione may be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Values of analytes vary lot to lot.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB3714 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable