Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

19697

Sigma-Aldrich

Vitamin K1 2,3-epoxide

≥98.0% (HPLC)

Sinônimo(s):

(2,3-Epoxyphytyl)menaquinone, 1a,7a-Dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecenyl)naphth[2,3-b]oxirene-2,7-dione, 2,3-Epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone, 2,3-Epoxyphylloquinone, Phylloquinone oxide

Faça loginpara ver os preços organizacionais e de contrato


About This Item

Fórmula empírica (Notação de Hill):
C31H46O3
Número CAS:
Peso molecular:
466.70
Número CE:
Código UNSPSC:
12352205
ID de substância PubChem:
NACRES:
NA.28

Nível de qualidade

Ensaio

≥98.0% (HPLC)

forma

(Liquid or Viscous Liquid)

cor

colorless to green-yellow
colorless to green
colorless to yellow

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O=C1C2(C/C=C(C)/CCCC(C)CCCC(C)CCCC(C)C)C(O2)(C)C(C3=CC=CC=C31)=O

InChI

1S/C31H46O3/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-31-29(33)27-19-8-7-18-26(27)28(32)30(31,6)34-31/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+

chave InChI

KUTXFBIHPWIDJQ-LKUDQCMESA-N

Ações bioquímicas/fisiológicas

Vitamin K1 2,3-epoxide is a vitamin K derivative. It is a fat soluble vitamin produced by plants. Vitamin K is essential for blood coagulation. Vitamin K is rarely deficient in a human diet since it is continually recycled in our cells. Vitamin K 2,3-epoxide acts as a substrate for vitamin K 2,3-epoxide reductase (VKOR) complex. Elevated levels of serum vitamin K epoxide in patients is associated with familial multiple coagulation factor deficiency.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Hereditary combined deficiency of the vitamin K-dependent clotting factors
Napolitano M, et al.
Orphanet Journal of Rare Diseases, 5(1), 21-21 (2010)
K Hirauchi et al.
Journal of chromatography, 430(1), 21-29 (1988-08-19)
A highly sensitive method for measuring endogenous vitamin K1, menaquinone-4 (which is one of the K2 vitamins) and vitamin K1 2,3-epoxide in human plasma was developed, based on high-performance liquid chromatography with coulometric reduction and fluorimetric detection, following extraction from
Metabolism of vitamin K1 (phylloquinone) in man
Barkhan P and Shearer MJ
Proceedings of the Royal Society of Medicine (1977)
Changes in the urinary metabolites of phylloquinone (vitamin K1) in man following therapeutic anticoagulation with warfarin.
A McBurney et al.
Biochemical pharmacology, 27(3), 273-278 (1978-02-01)
Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis
Shearer MJ and Newman P
Journal of Lipid Research, 55(3), 345-362 (2014)

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica