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Key Documents

Z0292

Sigma-Aldrich

α-Zearalanol

~98% (HPLC)

Sinônimo(s):

2,4-Dihydroxy-6-(6α,10-dihydroxyundecyl)benzoic acid μ-lactone

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About This Item

Fórmula empírica (Notação de Hill):
C18H26O5
Número CAS:
Peso molecular:
322.40
Número CE:
Número MDL:
Código UNSPSC:
12352200
ID de substância PubChem:
NACRES:
NA.77

fonte biológica

synthetic (organic)

Nível de qualidade

esterilidade

non-sterile

Ensaio

~98% (HPLC)

forma

powder

controle de medicamentos

regulated under CDSA - not available from Sigma-Aldrich Canada

técnica(s)

UHPLC: suitable

solubilidade

methanol: 1.96-2.04 mg/mL, clear, colorless to faintly yellow

Condições de expedição

ambient

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1

chave InChI

DWTTZBARDOXEAM-GXTWGEPZSA-N

Pictogramas

CorrosionHealth hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Repr. 2 - Skin Corr. 1B

Código de classe de armazenamento

8A - Combustible, corrosive hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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C Mastri et al.
Journal of steroid biochemistry, 23(3), 279-289 (1985-09-01)
It is now well established that the mycotoxin zearalenone and some of its derivatives possess oestrogenic activity. In the present study, the binding characteristics of [3H]zearalanol (P-1496) to different classes of sites including [1] the oestrogen receptor, [2] the higher
Angela Filannino et al.
Reproductive biology and endocrinology : RB&E, 9, 134-134 (2011-10-06)
The aim of this study was to investigate the in vitro effects of the Fusarium fungus-derived mycotoxin, zearalenone and its derivatives alpha-zearalenol and beta-zearalenol on motility parameters and the acrosome reaction of stallion sperm. Since the toxic effects of zearalenone
Shen Qu et al.
Environmental science & technology, 46(24), 13202-13211 (2012-11-21)
Trenbolone acetate, melengestrol acetate, and zeranol are synthetic hormones extensively used as growth promoters in animal agriculture, yet despite occurrence in water and soil little is known about their environmental fate. Here, we establish the time scales and mechanisms by
A Pazaiti et al.
International journal of clinical practice, 66(1), 28-36 (2011-12-08)
Zearalenone (ZEN) is a non-steroidal mycoestrogen that widely contaminates agricultural products. ZEN and its derivatives share similar molecular mechanisms and activity with estrogens and interact with ERα and ERβ leading to changes in the reproductive system in both animals and
Stefanie C Fleck et al.
Toxicology letters, 210(1), 9-14 (2012-01-31)
α-Zearalanol (α-ZAL, zeranol) is a highly estrogenic macrocyclic β-resorcylic acid lactone, which is used as a growth promotor for cattle in various countries. We have recently reported that α-ZAL and its major metabolite zearalanone (ZAN) are hydroxylated at the aromatic

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