Pular para o conteúdo
Merck
Todas as fotos(4)

Key Documents

View All Documentation

V1255

Sigma-Aldrich

D-Valine

BioReagent, suitable for cell culture

Sinônimo(s):

(R)-α-Aminoisovaleric acid, D-2-Amino-3-methylbutanoic acid

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(4)

About This Item

Fórmula linear:
(CH3)2CHCH(NH2)CO2H
Número CAS:
640-68-6
Peso molecular:
117.15
Beilstein:
1721135
Número CE:
211-368-9
Número MDL:
MFCD00064219
Código UNSPSC:
12352209
ID de substância PubChem:
24900713
NACRES:
NA.75

fonte biológica

synthetic (organic)

Nível de qualidade

200

linha de produto

BioReagent

forma

powder

técnica(s)

cell culture | mammalian: suitable

pf

>295 °C (subl.) (lit.)

Condições de expedição

ambient

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

CC(C)[C@@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1

chave InChI

KZSNJWFQEVHDMF-SCSAIBSYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine.

Aplicação

D-Valine has been used as a supplement in:
  • Dulbecco′s modified Eagle′s medium (DMEM)/Nutrient Mixture F-12 Ham (F-12) for mice renal proximal tubule cell (RPTC) culture
  • endothelial cell growth medium MV2 for rat lung microvascular endothelial cell (RLMEC) culture
  • DMEM/F-12 for mouse tracheal epithelial cell (MTEC) culture

Ações bioquímicas/fisiológicas

D-Valine has a broad range of industrial applications such as semi-synthetic veterinary antibiotics, pharmaceutical drugs, and agricultural pesticides.
D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 5

1 of 5

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) powder

Sigma-Aldrich

E3257

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester)

D-Serine ≥98% (TLC)

Sigma-Aldrich

S4250

D-Serine

D-Proline ReagentPlus®, ≥99%

Sigma-Aldrich

858919

D-Proline

D-Alanine ≥98% (HPLC)

Sigma-Aldrich

A7377

D-Alanine

L-leucina reagent grade, ≥98% (HPLC)

Sigma-Aldrich

L8000

L-leucina

Elham Mohammadi et al.
Cell and tissue research, 362(3), 597-609 (2015-06-13)
Efficacy of therapeutic angiogenesis needs a comprehensive understanding of endothelial cell (EC) function and biological factors and cells that interplay with ECs. Stem cells are considered the key components of pro- and anti-angiogenic milieu in a wide variety of physiopathological
V A Lazzaro et al.
Research communications in chemical pathology and pharmacology, 75(1), 39-48 (1992-01-01)
A selective cell culture medium, D-valine minimal essential medium (92 mg/l), has been developed to inhibit the proliferation of fibroblasts in cell culture (Gilbert & Migeon 1975). Substitution of D-valine for L-valine prevents fibroblast growth due to the absence of
Ming Chen et al.
World journal of microbiology & biotechnology, 32(10), 171-171 (2016-08-28)
D-Valine is an important organic chiral source and has extensive industrial application, which is used as intermediate for the synthesis of agricultural pesticides, semi-synthetic veterinary antibiotics and pharmaceutical drugs. Its derivatives have shown great activity in clinical use, such as
Hui Li et al.
PLoS pathogens, 14(1), e1006821-e1006821 (2018-01-05)
The highly pathogenic avian influenza (HPAI) H5N1 influenza virus has been a public health concern for more than a decade because of its frequent zoonoses and the high case fatality rate associated with human infections. Severe disease following H5N1 influenza
Phillip C Calder
The Journal of nutrition, 136(1 Suppl), 288S-293S (2005-12-21)
Although there has been great interest in the effects of amino acids on immune function, little is known about the impact of changes in BCAA availability on the ability of the immune system to function. Human immune cells incorporate BCAA
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica