U6750

Uridine 5′-triphosphate trisodium salt hydrate

Type IV, ≥93.0% (HPLC)

• Sinônimo(s): UTP Na₃
• Fórmula empírica (Notação de Hill): C₉H₁₂N₂Na₃O₁₅P₃ · xH₂O
• Número CAS: 19817-92-6
• Peso molecular: 550.09 (anhydrous basis)
• Beilstein: 3585234
• Número CE: 243-347-5
• Número MDL: MFCD00044310
• Código UNSPSC: 12352200
• ID de substância PubChem: 24900658
• NACRES: NA.77

Propriedades

• tipo: Type IV
• Nível de qualidade: 200
• Ensaio: ≥93.0% (HPLC)
• solubilidade: H₂O: soluble 25 mg of UTP in 0.5 ml of solvent, clear, colorless
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
• chave InChI: MMJGIWFJVDOPJF-LLWADOMFSA-K

Descrição

Aplicação

UTP has been used as a P2 receptor activator to study its effects on proton efflux in MC3T3-E1 and UMR-106 cells. UTP has also been studied in combination with amiloride hydrochloride in nebulizer solutions for treating cystic fibrosis.

Uridine 5′-triphosphate has been used in a study to show that fluoxetine (FLX), mediates its anti-depressive effect by increasing the gliotransmission of adenosine 5′-triphosphate (ATP).

Ações bioquímicas/fisiológicas

Uridine-5′-Triphosphate (UTP) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate (UTP) is involved in various pathophysiological responses in the nervous system. UTP also plays a major role in the regeneration process.

P2Y receptor agonist.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Nota de preparo

25 mg of Uridine 5′-triphosphate trisodium salt (UTP Na₃) hydrate is soluble in 0.5 ml of water and yields a clear, colorless solution.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)