U1006

Uridine 5′-triphosphate trisodium salt solution

HPLC purified, aqueous solution for RNA polymerase transcription

• Sinônimo(s): UTP
• Número MDL: MFCD00044310
• Código UNSPSC: 41106305
• ID de substância PubChem: 24900622
• NACRES: NA.52

Propriedades

• fonte biológica: yeast (Candida Utilis)
• Nível de qualidade: 300
• Ensaio: ≥95 (HPLC)
• forma: liquid
• concentração: 100 mM in H₂O (adjusted to pH 7 with Trizma^®; base)
• cor: colorless
• atividade externa: DNase and RNase, none detected
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
• chave InChI: MMJGIWFJVDOPJF-LLWADOMFSA-K
• Informações sobre genes: human ... P2RY2(5029) ; rat ... P2ry2(29597)

Descrição

Aplicação

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca²⁺ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).

Ações bioquímicas/fisiológicas

UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.

Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

Informações legais

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable