A6419

Adenosina 5′-trifosfato

microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)

• Sinônimo(s): ATP
• Fórmula empírica (Notação de Hill): C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O
• Número CAS: 34369-07-8
• Peso molecular: 551.14 (anhydrous basis)
• Número MDL: MFCD00150755
• Código UNSPSC: 12352207
• eCl@ss: 32160414
• ID de substância PubChem: 24891086
• NACRES: NA.75

Propriedades

• fonte biológica: microbial
• Nível de qualidade: 200
• linha de produto: BioReagent
• Ensaio: ≥99% (HPLC)
• forma: powder
• técnica(s): cell culture | mammalian: suitable
• solubilidade: H₂O: 50 mg/mL
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• chave InChI: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Descrição

Descrição geral

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

Aplicação

Adenosine 5′-triphosphate disodium salt hydrate has been used:

• as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites
• in inflammasome activation assays in bone marrow derived macrophages
• for the stimulation of macrophages
• in nucleotide synthesis

Ações bioquímicas/fisiológicas

Agonista purinérgico P₂; aumenta a atividade dos canais de K⁺ ativados por Ca²⁺; substrato de sistemas enzimáticos dependentes de ATP

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type N95 (US)