A8937

Adenosine 5′-triphosphate dipotassium salt hydrate

from microbial, ≥92% (HPLC)

• Sinônimo(s): ATP, 5′-ATP-K₂
• Fórmula empírica (Notação de Hill): C₁₀H₁₄K₂N₅O₁₃P₃ · xH₂O
• Número CAS: 42373-41-1
• Peso molecular: 583.36 (anhydrous basis)
• Código UNSPSC: 41106305
• eCl@ss: 32160414
• ID de substância PubChem: 24891383
• NACRES: NA.51

Propriedades

• fonte biológica: microbial
• Nível de qualidade: 200
• Ensaio: ≥92% (HPLC)
• forma: powder
• solubilidade: H₂O: 50 mg/mL
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [K+].[K+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

Descrição

Descrição geral

Adenosine 5′-triphosphate (ATP) is synthesized in mitochondria by oxidative phosphorylation.

Aplicação

Adenosine 5′-triphosphate dipotassium salt hydrate has been used:

• in in vitro transcription reaction as nucleotide source and in 2x RNA binding buffer
• as a component of energy solution for calibrating crude cell extract
• to test its dependency with PK11195 in mediating autophagy

Ações bioquímicas/fisiológicas

Adenosine 5′-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is used in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. Metabolic disorders lead to ATP deficiency. Use of xanthine oxidoreductase inhibitors and inosine improves intracellular ATP levels.

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems.

Atenção

For maximum stability, store as frozen solution at pH 3.5 to 6.8.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves