Pular para o conteúdo
Merck
Todas as fotos(6)

Documentos

T4009

Sigma-Aldrich

Taurocholic acid sodium salt hydrate

≥95% (HPLC)

Sinônimo(s):

2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide, Sodium taurocholate hydrate

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(6)

About This Item

Fórmula empírica (Notação de Hill):
C26H44NNaO7S · xH2O
Número CAS:
345909-26-4
Peso molecular:
537.68 (anhydrous basis)
Número CE:
205-653-7
Número MDL:
MFCD00150819
Código UNSPSC:
12161900
ID de substância PubChem:
24900186
NACRES:
NA.25

fonte biológica

synthetic (organic)

Nível de qualidade

200

descrição

anionic

Ensaio

≥95% (HPLC)

forma

powder

peso molecular

micellar avg mol wt 2100

número de agregação

4

CMC

3-11 mM (20-25°C)

grupo funcional

sulfonic acid

Condições de expedição

ambient

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

[Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O

InChI

1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1

chave InChI

RDAJAQDLEFHVNR-NEMAEHQESA-M

Procurando produtos similares? Visita Guia de comparação de produtos

Categorias relacionadas

Descrição geral

Taurocholic acid sodium salt hydrate is a bile acid with detergent capabilities.

Aplicação

Taurocholic acid sodium salt hydrate has been used in a study to assess the adsorption of bile acids and salts to vegetable fibrous tissue. It has also been used in a study to investigate a method for determination of conjugated and unconjugated bile salts in serum and jejunal fluid.
Anionic detergent used for protein solubilization.

Ações bioquímicas/fisiológicas

Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.

Nota de preparo

Synthesized from cholic acid

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 5

1 of 5

Cholic acid from bovine and/or ovine, ≥98%

Sigma-Aldrich

C1129

Cholic acid

Sigma-Aldrich

Sigma-Aldrich

CBA

Bile acids, conjugated

Sodium taurolithocholate

Sigma-Aldrich

T7515

Sodium taurolithocholate

Chenodeoxycholic acid

Sigma-Aldrich

C9377

Chenodeoxycholic acid

Taurocholic Acid, Sodium Salt ULTROL® Grade, ≥98% (TLC), detergent to solubilize membrane-bound proteins in their native state

Millipore

580218

Taurocholic Acid, Sodium Salt

Joseph J Orsini et al.
Clinica chimica acta; international journal of clinical chemistry, 413(15-16), 1270-1273 (2012-05-03)
We sought to modify a previously published tandem mass spectrometry method of screening for 5 lysosomal storage disorders (LSDs) in order to make it better suited for high-throughput newborn screening. Two 3-mm dried blood spot (DBS) punches were incubated, each
Studies on the adsorption of bile salts to non-absorbed components of diet.
M A Eastwood et al.
Biochimica et biophysica acta, 152(1), 165-173 (1968-01-10)
A Tangerman et al.
Clinica chimica acta; international journal of clinical chemistry, 159(2), 123-132 (1986-09-15)
A reliable method is described for the determination of conjugated and unconjugated bile acids in serum and jejunal fluid. Bile acids are extracted using reverse-phase octadecylsilane bonded silica cartridges and are separated into their unconjugated and conjugated fractions using the
Theresa D Ho et al.
Infection and immunity, 82(6), 2345-2355 (2014-03-26)
Clostridium difficile is a clinically important pathogen and the most common cause of hospital-acquired infectious diarrhea. Expression of the C. difficile gene csfV, which encodes σ(V), an extracytoplasmic function σ factor, is induced by lysozyme, which damages the peptidoglycan of
Studies on the Antibacterial Properties of the Bile Acids and some Compounds Derived from Cholanic Acid
M. Stacey and M. Webb
Proc. Royal Soc. Lond. B., 134, 523-523 (1947)
Exibir todos os documentos relacionados

Artigos

Probiotics and Human Health

Today, diverse studies report the benefits of probiotics, such as inhibitory effects on pathogens, aid in the management or prevention of chronic intestinal inflammatory diseases or atopic syndromes, and support to the immune system. Potential beneficial applications abound, researchers continue to evaluate the effictiveness and clarify the mechanisms of action of probiotics.

Protocolos

Fast and Robust HPLC Separation of Bile Acids and Conjugates with Ascentis Express C18

This method is particularly useful in research into the role of individual bile acids as signaling molecules; suitable for clinical laboratories to investigate potential mechanisms linked to gut hormone profiles and glycemic control.

Conteúdo relacionado

Bile Acids Kit for LC-MS

Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes.

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica