SRP6172

IL-4 human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

• Sinônimo(s): B-cell stimulatory factor 1 (BSF-1), BCGF, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• fonte biológica: human
• recombinante: expressed in HEK 293 cells
• Ensaio: ≥95% (SDS-PAGE)
• forma: lyophilized
• peso molecular: (14 and 19 kDa, monomer)
• embalagem: pkg of 10 μg
• técnica(s): cell culture | mammalian: suitable
• nº de adesão NCBI: P05112
• Condições de expedição: dry ice
• temperatura de armazenamento: −70°C
• Informações sobre genes: human ... IL4(3565)

Descrição

Descrição geral

Interleukin-4 (IL-4) is a pleiotropic cytokine and a potent lymphoid cell growth factor. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The gene encoding this protein is localized on human chromosome 5q31.1. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Ações bioquímicas/fisiológicas

Interleukin-4 (IL-4) stimulates the growth and survivability of certain B cells and T cells. The interleukin 4 receptor also binds to interleukin-13 (IL-13), which may contribute to many overlapping functions of this cytokine and IL-13. STAT6 (signal transducer and activator of transcription-6) has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This protein exhibits anti-inflammatory responses and has a role in immune processes by protecting against intracellular pathogens.

forma física

Lyophilized from a solution of 20 mM Tris-HCl, pH 7.4, with 300 mM NaCl.

Nota de preparo

Centrifuge the vial prior to opening.

Reconstituição

Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable