SML1172

FFN102

≥98% (HPLC)

• Sinônimo(s): 4-(2-Amino-ethyl)-6-chloro-7-hydroxy-chromen-2-one trifluoroacetate, 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one trifluoroacetate, Mini 102, Mini102
• Fórmula empírica (Notação de Hill): C₁₁H₁₀ClNO₃ · CF₃CO₂H
• Número CAS: 1234064-11-9
• Peso molecular: 353.68
• Código UNSPSC: 12352200
• ID de substância PubChem: 329825700
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• forma: powder
• condição de armazenamento: desiccated
• cor: white to light brown
• solubilidade: DMSO: 10 mg/mL, clear
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: FC(F)(F)C(O)=O.NCCC(C1=CC(Cl)=C(O)C=C1O2)=CC2=O
• InChI: 1S/C11H10ClNO3.C2HF3O2/c12-8-4-7-6(1-2-13)3-11(15)16-10(7)5-9(8)14;3-2(4,5)1(6)7/h3-5,14H,1-2,13H2;(H,6,7)
• chave InChI: OGHPXKAKVMJGQH-UHFFFAOYSA-N

Descrição

Ações bioquímicas/fisiológicas

FFN102 is a pH-responsive fluorescent false neurotransmitter that acts as a dopamine transporter substrate (DAT) and also a substrate for vesicular monoamine transporter 2 (VMAT2). FFN102 selectively labels dopamine cell bodies and dendrites in ventral midbrain and dopaminergic synaptic terminals in dorsal striatum. Its greater fluorescence emission in neutral than acidic environments allows the visualization of dopamine release at individual presynaptic terminals and in situ pH measurement of catecholamine secretory vesicles.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable