SML0804

(S)-CPP sodium salt

≥96% (HPLC)

• Sinônimo(s): (S)-2-Chloro-3-phenylpropanoic acid sodium salt, (aS)-a-chloro-benzenepropanoic acid sodium salt
• Fórmula empírica (Notação de Hill): C₉H₈ClO₂ · Na
• Número CAS: 194979-70-9
• Peso molecular: 206.60
• Número MDL: MFCD28118980
• Código UNSPSC: 12352200
• ID de substância PubChem: 329825602
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥96% (HPLC)
• Formulário: powder
• cor: white to beige
• solubilidade: H₂O: 20 mg/mL, clear
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [O-]C([C@@H](Cl)CC1=CC=CC=C1)=O.[Na+]
• InChI: 1S/C9H9ClO2.Na/c10-8(9(11)12)6-7-4-2-1-3-5-7;/h1-5,8H,6H2,(H,11,12);/q;+1/p-1/t8-;/m0./s1
• chave InChI: HMHPCHNNVOLTFC-QRPNPIFTSA-M

Descrição

Ações bioquímicas/fisiológicas

(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase.

(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase. BDK is a negative regulator of BCKDC activity. Inhibition of BDK by (S)-CPP (IC₅₀ = 6.3 μM) leads to complex activation, and significant reduction of plasma levels of leucine/isoleucine and valine in wild type mice.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable