Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

SML0295

Sigma-Aldrich

Dihydromyricetin

≥98% (HPLC)

Sinônimo(s):

(2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one, 3,3′,4′,5,5′,7-Hexahydroxyflavanone, Ampelopsin, Ampeloptin, DHM

Faça loginpara ver os preços organizacionais e de contrato


About This Item

Fórmula empírica (Notação de Hill):
C15H12O8
Número CAS:
Peso molecular:
320.25
Número MDL:
Código UNSPSC:
12352200
ID de substância PubChem:
NACRES:
NA.77

Ensaio

≥98% (HPLC)

Formulário

powder

condição de armazenamento

protect from light

cor

white to beige

solubilidade

DMSO: ≥5 mg/mL (warmed)

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(C(O)=C3)O)[C@H]1O

InChI

1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1

chave InChI

KJXSIXMJHKAJOD-LSDHHAIUSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

Dihydromyricetin is a major flavonoid present in A. grossedentata.

Aplicação

Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.

Ações bioquímicas/fisiológicas

Dihydromyricetin (Ampelopsin) is a flavanonol with antioxidant and anti-cancer activity, found to have anti-alcohol intoxication effects. Its anti-alcohol effects appear to be by its actions as a positive modulator of GABA-A receptors at the benzodiazepine site.
Dihydromyricetin (Ampelopsin) is a flavanonol with antioxidant and anti-cancer activity.
Dihydromyricetin possesses anti-inflammatory action.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 5

1 of 5

Myricetin ≥96.0% (HPLC)

Sigma-Aldrich

70050

Myricetin

Myricitrin ≥99.0% (HPLC)

Sigma-Aldrich

91255

Myricitrin

Hispidulin ≥98% (HPLC)

Sigma-Aldrich

SML0582

Hispidulin

α-Mangostin ≥98% (HPLC)

Sigma-Aldrich

M3824

α-Mangostin

ε-Viniferin phyproof® Reference Substance

PHL83550

ε-Viniferin

Yanjun Shi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 87, 251-257 (2011-12-20)
The interaction between bovine serum albumin (BSA) and the anticancer drug molecule ampelopsin (AMP) was investigated using fluorescence spectroscopy, circular dichroism (CD) spectra, and time-resolved spectra under simulated physiological conditions. Fluorescence data showed that the intrinsic fluorescence of BSA was
Wei-Ming Zhou et al.
Molecules (Basel, Switzerland), 15(4), 2114-2123 (2010-04-30)
This study reports two novel 5-fluorouracil-substituted ampelopsin derivatives. The structures of two new derivatives were characterized by elemental analysis, 1H-NMR, 13C-NMR, IR and MS. Their anticancer activities in vitro against two cancer cell lines, K562 and K562/ADR, were investigated using
Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down-regulation of phosphorylation of PPARgamma in 3T3-L1 cells
Liu L, et al.
Journal of Cellular and Molecular Medicine, 22(2), 1247-1256 (2018)
Shimei Qi et al.
International immunopharmacology, 12(1), 278-287 (2011-12-24)
Ampelopsin (AMP), a plant flavonoid, has potent anti-inflammatory properties in vitro and in vivo. The molecular mechanisms of ampelopsin on pharmacological and biochemical actions of RAW264.7 macrophages in inflammation have not been clearly elucidated yet. In the present study, non-cytotoxic
Feng Ni et al.
PloS one, 7(6), e38802-e38802 (2012-06-14)
The objective of this study was to evaluate the chemopreventive effect of a novel flavonoid, ampelopsin (AMP) on the growth and metastasis of prostate cancer cells. AMP showed the more potent activity in inhibiting the proliferation of androgen-sensitive LNCaP and

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica