SAB4504099

Anti-phospho-PKC-pan (pThr⁴⁹⁷) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-PKCL, Anti-PRKCL, Anti-nPKC-eta
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 76 kDa
• reatividade de espécies: rat, mouse, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: P05129; P05771; P17252; P24723; Q02156; Q04759; Q05513; Q05655
• nº de adesão UniProt: P24723
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pThr497)
• Informações sobre genes: human ... PRKCA(5578) , PRKCB(5579) , PRKCD(5580) , PRKCE(5581) , PRKCG(5582) , PRKCH(5583) , PRKCQ(5588) , PRKCZ(5590)

Descrição

Descrição geral

Protein kinase C is a member of the cAMP-dependent, cGMP-dependent, and protein kinase C (AGC) superfamily of protein kinases. It has more than14 isoforms. A catalytic domain with an ATP binding site and a substrate-binding site is found in all PKC isoforms.

Imunogênio

The antiserum was produced against synthesized peptide derived from human PKC-pan around the phosphorylation site of Thr497.

Immunogen Range: 623-672

Aplicação

Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit has been used in western blot analysis (1:500).

Ações bioquímicas/fisiológicas

Protein kinase Cs (PKCs) are involved in the growth and function of the gastrointestinal tract and the immune response. PKCs regulates cyclins, cyclin-dependent kinases (cdks), cdk inhibitors, and cell division cycle 25 (cdc25) phosphatases.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable