PRKCH
protein kinase C, eta
Synonyms:
PKC-L, PKCL, PRKCL, nPKC-eta
Species:
Human PRKCH (5583), Mouse Prkch (18755), Rat Prkch (81749), cow PRKCH (518542), sheep PRKCH (101105574), naked mole-rat Prkch (101716769), Domestic Rabbit PRKCH (100344184), domestic guinea pig Prkch (100736222), chicken PRKCH (423518), Horse PRKCH (100051560) ...More
UniProtKB ID:
Gene ID:
- Human(5583) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq, Jul 2008]
- Mouse(18755) protein kinase C, eta
- Rat(81749) protein kinase C, eta
- cow(518542) protein kinase C, eta
- sheep(101105574) protein kinase C, eta
- naked mole-rat(101716769) protein kinase C, eta
- Domestic Rabbit(100344184) protein kinase C, eta
- domestic guinea pig(100736222) protein kinase C, eta
- chicken(423518) protein kinase C, eta
- Horse(100051560) protein kinase C, eta
- domestic cat(101082413) protein kinase C, eta
- dog(490722) protein kinase C, eta
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Small Molecule - Agonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PRKCH antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-phospho-PKCη (Thr655) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
PKCη, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
PKC η Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKC eta. For use in Kinase Assays.,
Species
human