SAB4300434

Anti-PAK1/PAK2/PAK3 (Ab-423/402/421) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-CDKN1A antibody produced in rabbit, Anti-MGC130000 antibody produced in rabbit, Anti-PAK65 antibody produced in rabbit, Anti-p21 protein (Cdc42 / Rac)-activated kinase 1 / 2 / 3 antibody produced in rabbit
• Número MDL: MFCD02097133
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: 61-67 kDa; 68-74 kDa
• reatividade de espécies: rat, human, mouse
• concentração: 1 mg/mL
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200
• Isotipo: IgG
• sequência de imunogênio: (R-S-T-M-V)
• nº de adesão NCBI: NP_001121638.1; NP_001122092.1; NP_002568.2
• nº de adesão UniProt: Q13177
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... PAK1(5058) , PAK2(5062) , PAK3(5063)

Descrição

Imunogênio

Peptide sequence around aa. 421-425/400-404/419-423 (R-S-T-M-V), according to the proteins PAK1/PAK2/PAK3.

Características e benefícios

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Descrição-alvo

The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable