SAB4504044

Anti-phospho-Myosin regulatory light chain 2 (pSer¹⁸) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-CMH10, Anti-MFM12, Anti-MLC-2s/v, Anti-MLC2
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 19 kDa
• reatividade de espécies: human, rat, mouse
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: P24844
• nº de adesão UniProt: P10916
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer18)
• Informações sobre genes: human ... MYL2(4633)

Descrição

Descrição geral

MYL2 (myosin light chain 2) encodes a myosin regulatory light chain (MLC-2V). It is made of two heavy chains, two essential light chains and two regulatory light chains. It is located on human chromosome 12q24.

Imunogênio

The antiserum was produced against synthesized peptide derived from human Myosin regulatory light chain 2 around the phosphorylation site of Ser18.

Immunogen Range: 3-52

Ações bioquímicas/fisiológicas

MYL2 (myosin light chain 2) helps to convert energy from ATP hydrolysis into mechanical force. This gene also plays a major role in the growth and progression of chronic HF (heart failure). Mutation in MYL2 gene result in infantile type I muscle fibre disease and cardiomyopathy.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable