PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
PAKalpha
Human PAK1 (5058), Mouse Pak1 (18479), Rat Pak1 (29431), Zebrafish pak1 (373103), domestic cat PAK1 (101087171), cow PAK1 (533729), dog PAK1 (607885), chicken PAK1 (419083), domestic guinea pig Pak1 (100714662), naked mole-rat Pak1 (101713465)
- Human(5058) Summary: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
- Mouse(18479) p21 protein (Cdc42/Rac)-activated kinase 1
- Rat(29431) p21 protein (Cdc42/Rac)-activated kinase 1
- Zebrafish(373103) p21/Cdc42/Rac1-activated kinase 1
- domestic cat(101087171) p21 protein (Cdc42/Rac)-activated kinase 1
- cow(533729) p21 protein (Cdc42/Rac)-activated kinase 1
- dog(607885) p21 protein (Cdc42/Rac)-activated kinase 1
- chicken(419083) p21 protein (Cdc42/Rac)-activated kinase 1
- domestic guinea pig(100714662) p21 protein (Cdc42/Rac)-activated kinase 1
- naked mole-rat(101713465) p21 protein (Cdc42/Rac)-activated kinase 1
- sheep(101111756) p21 protein (Cdc42/Rac)-activated kinase 1
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Antibodies
Monoclonal Anti-PAK1 antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
human
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-PAK1/2/3 (pThr423) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
human
western blot
Anti-phospho-PAK1 (pSer199) antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-PAK1/2/3 (pSer141) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
human
western blot
Anti-PAK1 antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
PAK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human