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Merck

PAK2

p21 protein (Cdc42/Rac)-activated kinase 2

Synonyms:
PAK65, PAKgamma
Species:
UniProtKB ID:
Gene ID:
  • Human(5062) Summary: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
  • Mouse(224105) p21 protein (Cdc42/Rac)-activated kinase 2
  • Rat(29432) p21 protein (Cdc42/Rac)-activated kinase 2
  • chicken(424860) p21 protein (Cdc42/Rac)-activated kinase 2
  • dog(612814) p21 protein (Cdc42/Rac)-activated kinase 2
  • domestic cat(101082845) p21 protein (Cdc42/Rac)-activated kinase 2
  • cow(513673) p21 protein (Cdc42/Rac)-activated kinase 2
  • domestic guinea pig(100713135) p21 protein (Cdc42/Rac)-activated kinase 2
  • naked mole-rat(101710712) p21 protein (Cdc42/Rac)-activated kinase 2
  • Domestic Rabbit(100009535) p21 protein (Cdc42/Rac)-activated kinase 2
  • sheep(101123517) p21 protein (Cdc42/Rac)-activated kinase 2

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-PAK2 (pSer141) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-PAK2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-PAK2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-PAK2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-PAK2 antibody produced in mouse, clone 1E1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay

western blot

Proteins

Product Number
Description
Species
PAK2, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PAK2,
Species
human
MISSION® esiRNA, targeting mouse Pak2,
Species
mouse