SAB4200742
Anti-c-Myc-Peroxidase antibody, Mouse monoclonal
clone 9E10, purified from hybridoma cell culture
Sinônimo(s):
Anti-MRTL, Anti-Myc, Anti-bHLHe39, Anti-v-myc avian myelocytomatosis viral oncogene homolog
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.56
Produtos recomendados
fonte biológica
mouse
Nível de qualidade
conjugado
peroxidase conjugate
forma do anticorpo
purified from hybridoma cell culture
tipo de produto de anticorpo
primary antibodies
clone
9E10, monoclonal
Formulário
lyophilized powder
reatividade de espécies
human
embalagem
vial of 100 μL
concentração
~2 mg/mL
técnica(s)
immunoblotting: 1:250-1:500 using lysate of HEK-293T cells over expressing c-Myc fusion protein
immunohistochemistry: suitable
Isotipo
IgG1
nº de adesão UniProt
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... MYC(4609)
Descrição geral
Monoclonal Anti-c-Myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with synthetic peptide of the human p62c-myc protein, conjugated to KLH. c-Myc is a proto-oncogene localized on long arm of human chromosome 8. The encoded protein contains an N-terminal transactivation domain. The human c-Myc proto-oncogene is the cellular homolog of the avian v-Myc gene found in several leukemogenic retroviruses.
Especificidade
Monoclonal Anti-Calponin specifically recognizes smooth muscle Calponin.
Imunogênio
Synthetic peptide of the human p62c-myc protein.
Aplicação
Anti-c-Myc-Peroxidase antibody, Mouse monoclonal may be used in immunoblotting and immunohistology.
Ações bioquímicas/fisiológicas
c-Myc is a transcription factor involved in regulation of cell growth, proliferation, differentiation and apoptosis. It is implicated in DNA replication, RNA splicing or transcription. Increased expression of the gene is associated with the development of various types of human cancers.
forma física
Supplied as lyophilized powder. After reconstitution with 0.1 mL of distilled water to a final antibody concentration of ∼ 2 mg/mL, the solution contains 1% BSA, 2.5% trehalose, 0.05% MIT in 0.01 M sodium phosphate buffered saline
Armazenamento e estabilidade
Store the lyophilized product at 2–8 °C. For extended storage after reconstitution, keep at –20 °C in working aliquots. Avoid repeated freeze-thaw cycles. For continuous use after reconstitution, keep at 2–8 °C for up to 1 month. Solutions at working dilution should be discarded if not used within 12 hours.
Exoneração de responsabilidade
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Skin Sens. 1
Código de classe de armazenamento
13 - Non Combustible Solids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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K Alitalo et al.
Nature, 306(5940), 274-277 (1983-11-17)
The myelocytomatosis viruses are a family of replication-defective avian retroviruses that cause a variety of tumours in chickens and transform both fibroblasts and macrophages in culture through the activity of their oncogene v-myc. A closely related gene (c-myc) is found
S Pelengaris et al.
Current opinion in genetics & development, 10(1), 100-105 (2000-02-19)
The protein products of many dominant oncogenes are capable of inducing both cell proliferation and apoptosis. Recent experiments employing transgenic mice that express an ectopically regulatable myc gene or protein have begun to elucidate the role of the balance between
Q Hu et al.
Science (New York, N.Y.), 268(5207), 100-102 (1995-04-07)
Phosphatidylinositol (Pl)-3 kinase is one of many enzymes stimulated by growth factors. A constitutively activated mutant, p110, that functions independently of growth factor stimulation was constructed to determine the specific responses regulated by Pl-3 kinase. The p110 protein exhibited high
Ann-Marie Baker et al.
Histopathology, 69(2), 222-229 (2016-01-31)
Recent attempts to study MYC distribution in human samples have been confounded by a lack of agreement in immunohistochemical staining between antibodies targeting the N-terminus and those targeting the C-terminus of the MYC protein. The aim of this study was
D Robertson et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 43(5), 471-480 (1995-05-01)
To determine the ultrastructural distribution of H-ras, the rho proteins rho-A, rho-B, rho-C, and the rac1 protein (members of the ras GTP-binding protein family), we used cDNA expression plasmids in which a short sequence coding for the epitope recognized by
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4200742-1VL | 4061833350966 |
| SAB4200742-500UL | 4065271044470 |
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