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S9692

Sigma-Aldrich

SU 6656

≥98% (HPLC)

Sinônimo(s):

2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide

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About This Item

Fórmula empírica (Notação de Hill):
C19H21N3O3S
Número CAS:
330161-87-0
Peso molecular:
371.45
Número MDL:
MFCD10565928
Código UNSPSC:
12352200
ID de substância PubChem:
24278818
NACRES:
NA.77

Nível de qualidade

100

Ensaio

≥98% (HPLC)

Formulário

powder

condição de armazenamento

protect from light
under inert gas

cor

orange-brown

solubilidade

DMSO: 12 mg/mL (orange solution)

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CN(C)S(=O)(=O)c1ccc2NC(=O)C(=C/c3cc4CCCCc4[nH]3)\c2c1

InChI

1S/C19H21N3O3S/c1-22(2)26(24,25)14-7-8-18-15(11-14)16(19(23)21-18)10-13-9-12-5-3-4-6-17(12)20-13/h7-11,20H,3-6H2,1-2H3,(H,21,23)/b16-10-

chave InChI

LOGJQOUIVKBFGH-YBEGLDIGSA-N

Informações sobre genes

human ... SRC(6714)

Categorias relacionadas

Ações bioquímicas/fisiológicas

SU 6656 is a selective Src family kinase inhibitor.
SU 6656 is a selective Src family kinase inhibitor. SU 6656 inhibits Src kinase in CD34 positively-selected umbilical cord blood cells.

Características e benefícios

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
074M4605V
091M4623V
119K46043
119K46042
119K46041

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Dioneia Araldi et al.
Pain, 158(7), 1204-1216 (2017-03-18)
We previously developed a model of opioid-induced neuroplasticity in the peripheral terminal of the nociceptor that could contribute to opioid-induced hyperalgesia, type II hyperalgesic priming. Repeated administration of mu-opioid receptor (MOR) agonists, such as DAMGO, at the peripheral terminal of
Roman Ginnan et al.
American journal of physiology. Cell physiology, 288(6), C1193-C1201 (2005-01-29)
Platelet-derived growth factor (PDGF) is an important regulator of vascular smooth muscle (VSM) cell growth and migration and has been identified as a key mediator of neointima formation resulting from vascular injury. PDGF exerts its effects, in part, through activation
Cecilia S Leung et al.
Nature communications, 5, 5092-5092 (2014-10-04)
Ovarian cancer is the most lethal gynaecologic malignancy in the United States, and advanced serous ovarian adenocarcinoma is responsible for most ovarian cancer deaths. However, the stroma-derived molecular determinants that modulate patient survival are yet to be characterized. Here we
Teemu Natunen et al.
Molecular neurodegeneration, 15(1), 66-66 (2020-11-11)
Alzheimer's disease (AD) is the most common neurodegenerative disease and type 2 diabetes (T2D) plays an important role in conferring the risk for AD. Although AD and T2D share common features, the common molecular mechanisms underlying these two diseases remain
Shutang Zhou et al.
American journal of physiology. Cell physiology, 290(2), C463-C471 (2005-09-16)
Cortactin, a predominant substrate of Src family kinases, plays an important role in Arp2/3-dependent actin polymerization in lamellipodia and membrane ruffles and was recently shown to be enriched in podosomes induced by either c-Src or phorbol ester. However, the mechanisms
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