S8701

SFLLR-NH2 trifluoroacetate salt

≥95% (HPLC), powder

• Sinônimo(s): L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-Arginine amide trifluoroacetate salt, Ser-Phe-Leu-Leu-Arg-amide trifluoroacetate salt, Thrombin Receptor Activator for Peptide 5 (TRAP-5) trifluoroacetate salt
• Fórmula empírica (Notação de Hill): C₃₀H₅₁N₉O₆ · xC₂HF₃O₂
• Número CAS: 1313730-13-0
• Peso molecular: 633.78 (free base basis)
• Número MDL: MFCD18782167
• Código UNSPSC: 12352200
• ID de substância PubChem: 329824608

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95% (HPLC)
• forma: powder
• cor: white to off-white
• solubilidade: H₂O: ≥2 mg/mL
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
• InChI: 1S/C30H51N9O6.C2HF3O2/c1-17(2)13-22(27(43)36-21(25(32)41)11-8-12-35-30(33)34)38-28(44)23(14-18(3)4)39-29(45)24(37-26(42)20(31)16-40)15-19-9-6-5-7-10-19;3-2(4,5)1(6)7/h5-7,9-10,17-18,20-24,40H,8,11-16,31H2,1-4H3,(H2,32,41)(H,36,43)(H,37,42)(H,38,44)(H,39,45)(H4,33,34,35);(H,6,7)/t20-,21-,22-,23-,24-;/m0./s1
• chave InChI: UUNMFWMQJXBTAA-VHIJBDTGSA-N

Descrição

Aplicação

SFLLR-NH2 trifluoroacetate salt may be used in cell signaling and immunology studies.

Ações bioquímicas/fisiológicas

SFLLR-NH2 is a PAR-1 (Protease-Activated Receptor) selective activating peptide, also known as Thrombin Receptor Activating Peptide 5 (TRAP-5). Protease-activated receptors (PARs) are present on various organs including, platelets, mast cell, gallblader, oesophagus etc, and regulate various physiological processes including human platelet aggregation, vascular contraction/relaxation, and an increase in endothelial permeability. Recent papers indicated that PAR′s are also involved in sensory processing and proliferation of astrocytes.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable