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S8502

Sigma-Aldrich

(−)-Scopolamine methyl bromide

≥98% (HPLC), powder

Sinônimo(s):

Hyoscine methyl bromide, Methscopolamine bromide

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About This Item

Fórmula empírica (Notação de Hill):
C18H24NO4 · Br
Número CAS:
155-41-9
Peso molecular:
398.29
Número CE:
205-844-5
Número MDL:
MFCD00078560
Código UNSPSC:
12352116
ID de substância PubChem:
24278714
NACRES:
NA.77

Ensaio

≥98% (HPLC)

forma

powder

atividade óptica

[α]25/D −25°, c = 5 in H2O(lit.)

cor

white

solubilidade

H2O: 50 mg/mL

cadeia de caracteres SMILES

[Br-].[H][C@]12C[C@@H](C[C@]([H])([C@@]3([H])O[C@@]13[H])[N+]2(C)C)OC(=O)[C@H](CO)c4ccccc4

InChI

1S/C18H24NO4.BrH/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11;/h3-7,12-17,20H,8-10H2,1-2H3;1H/q+1;/p-1/t12-,13-,14-,15+,16-,17+;/m1./s1

chave InChI

CXYRUNPLKGGUJF-RAFJPFSSSA-M

Informações sobre genes

human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

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Aplicação

(−)-Scopolamine methyl bromide was administered to rats to inhibit the peripheral cholinergic effects induced by pilocarpine.10,11

Ações bioquímicas/fisiológicas

Competitive muscarinic acetylcholine receptor antagonist.
Scopolamine is an anti-muscarinic and cholinolytic alkaloid that inhibits parasympathetic-cholinergic system.7 The central effects include hallucinations, disorientation, restlessness and euphoria.8 Scopolamine disturb the stimulus detection performance in rats by interfering with the reticular cholinergic pathways.9

Atenção

Shelf-life of the powder is at least five years when stored at room temperature.

Pictogramas

Exclamation markEnvironment
GHS07,GHS09

Palavra indicadora

Warning

Frases de perigo

H312 + H332,H400

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Acute 1

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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