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Key Documents

PHG0004

SAFC

BIS-TRIS

Fabricação farmacêutica

Sinônimo(s):

2,2-Bis(hidroximetil)-2,2′,2″-nitrilotrietanol, 2-Bis(2-hidroxietil)amino-2-(hidroximetil)-1,3-propanodiol, Bis(2-hidroxietil)amino-tris(hidroximetil)metano

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About This Item

Fórmula empírica (Notação de Hill):
C8H19NO5
Número CAS:
Peso molecular:
209.24
Beilstein:
2205275
Número CE:
Número MDL:
Código UNSPSC:
12161705
NACRES:
NA.21

fonte biológica

synthetic

Nível de qualidade

forma

powder

técnica(s)

cell culture | mammalian: suitable

Impurezas

Endotoxin, microbial, and trace metals; tested

faixa de pH útil

5.8-7.2

pKa (25 °C)

6.5

solubilidade

H2O: 0.1 M, clear, colorless

adequação

suitable for manufacturing use

atividade externa

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

cadeia de caracteres SMILES

OCCN(CCO)C(CO)(CO)CO

InChI

1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2

chave InChI

OWMVSZAMULFTJU-UHFFFAOYSA-N

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Descrição geral

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Aplicação

Bis Tris is a commonly used biological buffer for very broad usage in biological systems such as diagnostics, electrophoresis and protein based bioprocessing. The pKa of Bis Tris is 6.36 which makes it a good candidate for biological-based formulations.

Bis Tris is used in a wide variety of biological applications including protein separation buffers, cell culture media, electrophoresis separations and diagnostic reagent formulations.

Informações legais

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

substituído por

Nº do produto
Descrição
Preços

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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