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PHG0007

SAFC

MOPS

Fabricação farmacêutica

Sinônimo(s):

Ácido 3-(N-morfolino) propanossulfônico, Ácido 4-morfolino propanossulfônico

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About This Item

Fórmula empírica (Notação de Hill):
C7H15NO4S
Número CAS:
1132-61-2
Peso molecular:
209.26
Beilstein:
1106776
Número CE:
214-478-5
Número MDL:
MFCD00006183
Código UNSPSC:
12161700
NACRES:
NA.21

fonte biológica

synthetic

Nível de qualidade

400

Ensaio

≥99.5%

forma

powder

técnica(s)

cell culture | mammalian: suitable

Impurezas

Endotoxin, microbial, and trace metals; tested

pH

2.5-4 (1 M in H2O)

faixa de pH útil

6.5-7.9

pKa (25 °C)

7.2

λ

1 M in H2O

adequação

suitable for manufacturing use

atividade externa

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

cadeia de caracteres SMILES

OS(=O)(=O)CCCN1CCOCC1

InChI

1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

chave InChI

DVLFYONBTKHTER-UHFFFAOYSA-N

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Descrição geral

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Aplicação

MOPS is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS is considered to be non-toxic to culture cell lines and provides high-solution clarity.

MOPS is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream). MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Informações legais

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

substituído por

Nº do produto
Descrição
Preços

137273

MOPS, EMPROVE® EVOLVE

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

230.0 °F - closed cup

Ponto de fulgor (°C)

110 °C - closed cup

Certificados de análise (COA)

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MOPS ≥99.5% (titration)

Sigma-Aldrich

M9381

MOPS

vibrant-m

D0738000

Dextran 40 for performance test

HEPES

SAFC

RES6003H-B7

HEPES

MOPS anhydrous, free-flowing, Redi-Dri™, ≥99.5%

Sigma-Aldrich

RDD018

MOPS

Pepstatina A microbial, ≥75% (HPLC)

Sigma-Aldrich

P4265

Pepstatina A

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Y S L Lee et al.
Human reproduction (Oxford, England), 30(3), 543-552 (2015-01-09)
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Sewa Rijal et al.
Blood, 125(18), 2815-2824 (2015-03-05)
Phosphoinositide signaling regulates diverse cellular functions. Phosphoinositide-3 kinase (PI3K) generates PtdIns(3,4,5)P3 and PtdIns(3,4)P2, leading to the activation of proliferative and anti-apoptotic signaling pathways. Termination of phosphoinositide signaling requires hydrolysis of inositol ring phosphate groups through the actions of PtdIns(3,4,5)P3 3-phosphatase
Sanna Byström et al.
Journal of proteome research, 13(11), 4607-4619 (2014-09-19)
The brain is a vital organ and because it is well shielded from the outside environment, possibilities for noninvasive analysis are often limited. Instead, fluids taken from the spinal cord or circulatory system are preferred sources for the discovery of
Alexandre Albanese et al.
ACS nano, 8(6), 5515-5526 (2014-05-07)
A nanoparticle's physical and chemical properties at the time of cell contact will determine the ensuing cellular response. Aggregation and the formation of a protein corona in the extracellular environment will alter nanoparticle size, shape, and surface properties, giving it
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