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P7780

Sigma-Aldrich

Propionylpromazine hydrochloride

Sinônimo(s):

Propiopromazine hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C20H24N2OS · HCl
Número CAS:
7681-67-6
Peso molecular:
376.94
Beilstein:
38502
Número MDL:
MFCD01941563
Código UNSPSC:
12352200
ID de substância PubChem:
24278651
NACRES:
NA.77

forma

powder

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Cl.CCC(=O)c1ccc2Sc3ccccc3N(CCCN(C)C)c2c1

InChI

1S/C20H24N2OS.ClH/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20;/h5-6,8-11,14H,4,7,12-13H2,1-3H3;1H

chave InChI

ZFWVWZODBGTOIL-UHFFFAOYSA-N

Informações sobre genes

human ... DRD2(1813)

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Ações bioquímicas/fisiológicas

Phenothiazine antipsychotic; D2 dopamine receptor antagonist.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

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Y Govaert et al.
The Analyst, 123(12), 2507-2512 (1999-08-06)
A rapid and sensitive multi-residue method was developed to attempt to confirm the presence of the beta-blocker carazolol and the tranquillizers acepromazine, azaperone, chlorpromazine, propionylpromazine and xylazine in pig muscle tissues. The procedure involves determination by liquid chromatography coupled with
Residues of some veterinary drugs in animals and foods. Monographs prepared by the thirty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives.
FAO food and nutrition paper, 41(4), 1-136 (1991-01-01)
M Olling et al.
Journal of veterinary pharmacology and therapeutics, 4(4), 291-294 (1981-12-01)
A thin-layer chromatographic method for the determination of the veterinary tranquillizer propiopromazine (Combelen) in slaughter pigs is described. Propiopromazine residue depletion from the kidney occurs with different rates in sows and in castrated boars. In the liver residues increase over
J Park et al.
Journal of chromatography, 489(2), 313-321 (1989-04-14)
The propionylpromazine concentrations in plasma after intramuscular administration to horses were determined using gas chromatography with nitrogen-phosphorus detection. After hydrolysis by beta-glucuronidase/arylsulphatase, the parent drug and three metabolites were detected in urine. The metabolites were identified as 2-(1-hydroxypropyl)promazine, 2-(1-propenyl)promazine and
D B Hurlbut et al.
Journal of AOAC International, 82(6), 1321-1328 (1999-12-10)
Propionylpromazine hydrochloride (PPZHCl) has been investigated for use with leghold traps to reduce the amount of self-inflicted trauma experienced by animals restrained by these traps. Three types of PPZHCl formulations made with Karo dark syrup, K-Y Jelly, and Vaseline were
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