P2870
Pristane
synthetic, ≥98% (GC)
Sinônimo(s):
Norphytane, 2,6,10,14-Tetramethylpentadecane
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About This Item
Fórmula linear:
(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)(CH2)3CH(CH3)2
Número CAS:
Peso molecular:
268.52
Beilstein:
1720538
Número CE:
Número MDL:
Código UNSPSC:
12352001
ID de substância PubChem:
NACRES:
NA.25
Produtos recomendados
fonte biológica
synthetic
Nível de qualidade
Ensaio
≥98% (GC)
Formulário
liquid
peso molecular
268.5
condição de armazenamento
(tightly closed)
cor
colorless
índice de refração
n20/D 1.438 (lit.)
p.e.
68 °C/0.001 mmHg (lit.)
solubilidade
hexane: miscible 10 % (v/v)
densidade
0.783 g/mL at 20 °C (lit.)
temperatura de armazenamento
room temp
cadeia de caracteres SMILES
CC(C)CCCC(C)CCCC(C)CCCC(C)C
InChI
1S/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3
chave InChI
XOJVVFBFDXDTEG-UHFFFAOYSA-N
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Descrição geral
Pristane, also known as norphytane, is a saturated norterpenoid alkane derived from phytane. Its immunological properties are valuable for various applications, serving as an inflammation-inducing agent in tumorigenesis and autoimmune disease induction, facilitating research on conditions like rheumatoid arthritis and lupus. Pristane′s diverse applications span acting as an immunological adjuvant, inducing autoimmune diseases, facilitating monoclonal antibody production, and serving as an energy source, making it a valuable asset in biochemical research, cell culture, and molecular biology.
Aplicação
Pristane also acts as an immunological adjuvant for generating monoclonal antibodies in mouse ascites and finds use as a biological marker. Additionally, pristane can also be used as the primary carbon and energy source for the growth of a bacterial strain, coryneform soil isolate. Its distinctive ability to induce plasmacytomas is particularly valuable for studying B-cell tumors like Burkitt′s lymphoma.
It is commonly used for priming animals, leading to granulomatous inflammation and disruption of local lymphatic drainage, resulting in increased ascitic yields. It has been used to induce systemic lupus in mice
It is commonly used for priming animals, leading to granulomatous inflammation and disruption of local lymphatic drainage, resulting in increased ascitic yields. It has been used to induce systemic lupus in mice
Pristane has been used as an inflammation-inducing agent, leading to myeloma development in BALB/c strain mice. It has been used as a rheumatoid arthritis-inducing agent in rats.
Características e benefícios
High quality compound suitable for multiple research applications
Outras notas
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Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Skin Irrit. 2
Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
>230.0 °F - closed cup
Ponto de fulgor (°C)
> 110 °C - closed cup
Equipamento de proteção individual
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.
Tuncel J
PLoS ONE, 11, e0155936-e0155936 (2016)
Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse.
Sanchez-Gonzalez B
Mediators of Inflammation, 2015, 313140-313140 (2015)
Marli L Moraes et al.
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The diagnostics of the autoimmune hemolytic anemia (AIHA), a rare disease caused by autoantibody-induced hemolysis, is still prone to false positives for it is based on visual observation in the so-called Direct Coombs test. In this study, we developed a
M Satoh et al.
Clinical and experimental immunology, 121(2), 399-405 (2000-08-10)
Unlike other agents associated with drug-induced lupus, the isoprenoid alkane pristane induces autoantibodies pathognomonic of lupus, including anti-Sm, anti-dsDNA, and anti-ribosomal P in BALB/c and SJL/J mice. The susceptibility of other strains of mice to pristane-induced lupus is unknown and
K Gadó et al.
Haematologica, 86(3), 227-236 (2001-03-20)
There is no ideal animal model for human multiple myeloma (MM). All the models resemble the human disease in some respect, but none of them fulfils all the criteria of a perfect animal model. The pristane oil (2,6,10,12-tetramethylpentadecane)-induced mouse plasmacytoma
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