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Documentos Principais

P1751

Sigma-Aldrich

D-Phenylalanine

≥98% (HPLC)

Sinônimo(s):

(R)-2-Amino-3-phenylpropionic acid

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About This Item

Fórmula empírica (Notação de Hill):
C9H11NO2
Número CAS:
Peso molecular:
165.19
Beilstein:
2804068
Número CE:
Número MDL:
Código UNSPSC:
12352209
ID de substância PubChem:
NACRES:
NA.26

Nome do produto

D-Phenylalanine, ≥98% (HPLC)

Nível de qualidade

Ensaio

≥98% (HPLC)

Formulário

powder

cor

white to off-white

pf

273-276 °C

aplicação(ões)

cell analysis

cadeia de caracteres SMILES

N[C@H](Cc1ccccc1)C(O)=O

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1

chave InChI

COLNVLDHVKWLRT-MRVPVSSYSA-N

Informações sobre genes

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Aplicação

<ul>
<li><strong>Paper Title: </strong> Supramolecular nanofibers co-loaded with dabrafenib and doxorubicin for targeted and synergistic therapy of differentiated thyroid carcinoma. D-Phenylalanine are used to improve the stability of peptides <em>in vivo</em> (Chen P et al., 2023).</li>
<li><strong>Paper Title: </strong> Mechanistic aspects of the transamination reactions catalyzed by D-amino acid transaminase from Haliscomenobacter hydrossis. This study focuses on the enzymatic roles of D-Phenylalanine in specific bacterial transamination processes, applicable in biocatalysis and synthetic biology (Bakunova AK et al., 2023).</li>
</ul>

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Sigma-Aldrich

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Sigma-Aldrich

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Jincheng Ni et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(2) (2020-12-30)
Spin angular momentum of light is vital to investigate enantiomers characterized by circular dichroism (CD), widely adopted in biology, chemistry, and material science. However, to discriminate chiral materials with multiscale features, CD spectroscopy normally requires wavelength-swept laser sources as well
Andrew T Schuster et al.
Gastroenterology, 148(7), 1405-1416 (2015-02-24)
Defects in colonic epithelial barrier defenses are associated with ulcerative colitis (UC). The proteins that regulate bacterial clearance in the colonic epithelium have not been completely identified. The Drosophila chromosome-associated protein D3 (dCAP-D3) regulates responses to bacterial infection. We examined
Suneela S Dhaneshwar et al.
European journal of medicinal chemistry, 44(1), 131-142 (2008-05-13)
Mutual amide prodrugs of 4-aminosalicylic acid with D-phenylalanine and L-tryptophan were synthesized for targeted drug delivery to the inflamed gut tissue in inflammatory bowel disease. Stability studies in aqueous buffers (pH 1.2 and 7.4) showed that the synthesized prodrugs were
Ruth Milkereit et al.
Nature communications, 6, 7250-7250 (2015-05-23)
Mammalian target of rapamycin 1 (mTORC1), a master regulator of cellular growth, is activated downstream of growth factors, energy signalling and intracellular essential amino acids (EAAs) such as Leu. mTORC1 activation occurs at the lysosomal membrane, and involves V-ATPase stimulation
Florian Beaumatin et al.
Molecular cell, 76(1), 163-176 (2019-09-08)
Sensing nutrient availability is essential for appropriate cellular growth, and mTORC1 is a major regulator of this process. Mechanisms causing mTORC1 activation are, however, complex and diverse. We report here an additional important step in the activation of mTORC1, which

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