P0359
Palmitoylethanolamide
≥98% (HPLC), powder, cannabinoid receptor agonist
Sinônimo(s):
N-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol
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About This Item
Fórmula empírica (Notação de Hill):
C18H37NO2
Número CAS:
Peso molecular:
299.49
Número CE:
Número MDL:
Código UNSPSC:
12352200
ID de substância PubChem:
NACRES:
NA.77
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Nome do produto
Palmitoylethanolamide,
Formulário
powder
Nível de qualidade
temperatura de armazenamento
−20°C
cadeia de caracteres SMILES
CCCCCCCCCCCCCCCC(=O)NCCO
InChI
1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
chave InChI
HXYVTAGFYLMHSO-UHFFFAOYSA-N
Informações sobre genes
human ... CNR1(1268) , CNR2(1269)
rat ... Faah(29347)
Aplicação
Palmitoylethanolamide has been used as a reference standard in mass spectrometry (MS/MS).
Ações bioquímicas/fisiológicas
Palmitoylethanolamide (PEA) is a natural fatty acid amide of ethanolamine and palmitic acid. It is found in soybeans, egg yolk, and many other food sources. PEA is an endogenous cannabinoid receptor agonist. It is a peroxisome proliferator-activated receptor α (PPAR-α) ligand. PEA possesses anti-inflammatory, anti-allergic, neuroprotective, and analgesic activities. It belongs to the class of lipid mediators and the N-acylethanolamine family. PEA blocks the release of pro-inflammatory mediators from activated mast cells and prevents the recruitment of activated mast cells at the site of nerve injury.
Ligação
Structural analog of anandamide.
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
Código de classe de armazenamento
13 - Non Combustible Solids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Current medicinal chemistry, 9(6), 663-674 (2002-04-12)
The discovery of anandamide as an endogenous ligand for the cannabinoid receptors has led to a resurgence of interest in the fatty acid amides. However, N-palmitoylethanolamine (PEA), a shorter and fully saturated analogue of anandamide, has been known since the
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Journal of chromatographic science, 54(8), 1428-1434 (2016-05-04)
This article aims to build up a simple, rapid and accurate capillary zone electrophoresis (CZE) method for the separation of biogenic amines (BAs). Here, 10 key BAs (phenethylamine, histamine, tryptamine, tyramine, 5-hydroxytryptamine, octopamine, dopamine, norepinephrine, epinephrine and carnosine) owning significant
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