O8382
17-Octadecynoic acid
≥95% (GC)
Sinônimo(s):
17-ODYA, Alkynyl Stearic Acid, Octadec-17-ynoic acid
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About This Item
Fórmula empírica (Notação de Hill):
C18H32O2
Número CAS:
Peso molecular:
280.45
Número MDL:
Código UNSPSC:
12352106
ID de substância PubChem:
NACRES:
NA.77
Produtos recomendados
Ensaio
≥95% (GC)
Formulário
powder
solubilidade
chloroform: 10 mg/mL to clear, colorless to faintly yellow
cadeia de caracteres SMILES
C#CCCCCCCCCCCCCCCCC(O)=O
InChI
1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h1H,3-17H2,(H,19,20)
chave InChI
DZIILFGADWDKMF-UHFFFAOYSA-N
Categorias relacionadas
Aplicação
17-Octadecynoic acid has been used in lipid synthesis.
Ações bioquímicas/fisiológicas
17-Octadecynoic acid (7-ODYA) is an irreversible inhibitor of cytochrome P450 isozymes, that participates in long-chain fatty acid metabolism.
Suicide substrate inhibitor that selectively and irreversibly inhibits cytochrome P450 epoxygenases and ω-hydrolases.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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American Journal of Hypertension, 11(7), 803-812 (1998)
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The Journal of pharmacology and experimental therapeutics, 284(3), 966-973 (1998-03-13)
We characterized the inhibitory activity of several acetylenic and olefinic compounds on cytochrome P450 (CYP)-derived arachidonic acid omega-hydroxylation and epoxidation using rat renal cortical microsomes and recombinant CYP proteins. Among the acetylenic compounds, 6-(2-propargyloxyphenyl)hexanoic acid (PPOH) and N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamide were found
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Sensitive and specific visualization of small biomolecules in living systems is highly challenging. We report stimulated Raman-scattering imaging of alkyne tags as a general strategy for studying a broad spectrum of small biomolecules in live cells and animals. We demonstrate
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American journal of physiology. Lung cellular and molecular physiology, 283(2), L383-L389 (2002-07-13)
We examined the responses of newborn piglet pulmonary resistance arteries (PRAs) to 5,6-epoxyeicosatrienoic acid (5,6-EET), a cytochrome P-450 metabolite of arachidonic acid. In PRAs preconstricted with a thromboxane A(2) mimetic, 5,6-EET caused a concentration-dependent dilation. This dilation was partially inhibited
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