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Documentos Principais

N5413

Sigma-Aldrich

Anti-Nestin antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Sinônimo(s):

Anti-FJ21841, Anti-NES, Anti-Nbla00170

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

buffered aqueous solution

peso molecular

antigen ~110 kDa (cleaved)
antigen ~177 kDa
antigen ~270 kDa

reatividade de espécies

rat, mouse, human

concentração

~1 mg/mL

técnica(s)

flow cytometry: 1:200-1:500
immunohistochemistry: 1:100-1:200
western blot: 1:500-1:1,000

nº de adesão UniProt

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... NES(10763)
mouse ... Nes(18008)
rat ... Nes(25491)

Descrição geral

Nestin (NES) is a class VI cytoplasmic protein. It is expressed in the intermediate filaments and has a molecular weight of 177kDa. The gene encoding it is localized on human chromosome 1q23.1 with four exons.

Imunogênio

synthetic peptide corresponding to residues 254-270 of human Nestin. This sequence is 93% identical in rat.

Ações bioquímicas/fisiológicas

Nestin (NES) functions as a regulator of proteins which are involved in cell growth. It also interacts with other proteins of the intermediate filament. NES has been studied as a marker of neural stem cells.

forma física

solution in phosphate buffered saline, containing 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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International journal of molecular medicine, 40(3), 814-824 (2017-07-18)
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Frequently asked questions about neural stem cells including NSC derivation, expansion and differentiation.

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