L8134
Linoleic acid sodium salt
≥97% (GC)
Sinônimo(s):
Sodium linolate, Sodium linoleate, cis-9,cis-12-Octadecadienoic acid sodium salt
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About This Item
Fórmula linear:
C18H31O2Na
Número CAS:
Peso molecular:
302.43
Número CE:
Número MDL:
Código UNSPSC:
12352211
ID de substância PubChem:
NACRES:
NA.25
Produtos recomendados
fonte biológica
plant oil (safflower)
Ensaio
≥97% (GC)
forma
powder
técnica(s)
activity assay: suitable
cor
white
pf
230 °C (446 °F)
solubilidade
methanol: 50 mg/mL, clear, yellow
aplicação(ões)
general analytical
life science and biopharma
grupo funcional
carboxylic acid
tipo de lipídio
omega FAs
Condições de expedição
ambient
temperatura de armazenamento
−20°C
cadeia de caracteres SMILES
[Na+].CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O
InChI
1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
chave InChI
WYPBVHPKMJYUEO-NBTZWHCOSA-M
Descrição geral
Linoleic acid, an essential omega-6 polyunsaturated fatty acid (PUFA), serves as a precursor to arachidonic acid (AA), necessary for synthesizing prostaglandins and other eicosanoids. Being an essential fatty acid, linoleic acid must be acquired through diet as the body cannot produce it. Deficiencies in linoleic acid are linked to health issues such as impaired wound healing, growth retardation, and dermatitis. Arachidonate 15 Lipoxygenase (15-LO) metabolizes linoleic acid in both plants and animals, forming 9- and 13-hydroxyoctadecadienoic acid (HODE). This versatile molecule finds applications in biochemical, metabolomics, and lipidomics research, enabling investigations into various metabolic pathways and providing insights into lipid functions in living organisms.
Aplicação
Linoleic acid sodium salt has been used:
- in the β-carotene-linoleic acid assay
- as a component in basal medium to treat peripheral blood mononuclear cells (PBMCs)
- in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 HEPES (4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid) to incubate human trophoblast-derived choriocarcinoma cells (BeWo) and study its effects on adherens junctions (AJ) marker level, cell layer permeability, and intracellular lipid accumulation
Ações bioquímicas/fisiológicas
Linoleic acid, as a component of acylglycosyl ceramides, plays a physiological role in maintaining the water permeability barrier of the skin. The deficiency of linoleic acid may cause poor growth or development, scaly dermatitis, and an impaired immune response in infants. It is used in cosmetic and personal care products. Linoleic acid is mainly used as emollients or moisturizers for skin, nails, and hair.
Características e benefícios
- High-quality molecule suitable for mulitple research applications
- Commonly employed in Metabolomics and Biochemical studies
Outras notas
For additional information on our range of Biochemicals, please complete this form.
Palavra indicadora
Warning
Frases de perigo
Classificações de perigo
Skin Irrit. 2
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Gloves
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