G2785

Glycitein

≥97% (HPLC)

• Sinônimo(s): 4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein
• Fórmula empírica (Notação de Hill): C₁₆H₁₂O₅
• Número CAS: 40957-83-3
• Peso molecular: 284.26
• Número MDL: MFCD00016679
• Código UNSPSC: 41106305
• ID de substância PubChem: 329799906
• NACRES: NA.51

Propriedades

• fonte biológica: synthetic (organic)
• Ensaio: ≥97% (HPLC)
• forma: powder
• solubilidade: DMF: 1 mg/mL, clear, colorless to faintly yellow
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: COc1cc2C(=O)C(=COc2cc1O)c3ccc(O)cc3
• InChI: 1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
• chave InChI: DXYUAIFZCFRPTH-UHFFFAOYSA-N

Descrição

Aplicação

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

Ações bioquímicas/fisiológicas

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

Glycitein possesses weak estrogenic activity than other soy isoflavones.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)