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C5423

Sigma-Aldrich

Clenbuterol hydrochloride

≥95% (TLC), powder, β2-adrenoceptor agonist

Sinônimo(s):

4-Amino-α-(t-butylaminomethyl)-3,5-dichlorobenzyl alcohol hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C12H18Cl2N2O · HCl
Número CAS:
21898-19-1
Peso molecular:
313.65
Número CE:
244-643-7
Número MDL:
MFCD00083280
Código UNSPSC:
12352200
ID de substância PubChem:
24892782
NACRES:
NA.77

Nome do produto

Clenbuterol hydrochloride, ≥95%

Nível de qualidade

200

Ensaio

≥95%

Formulário

powder

drug control

Home Office Schedule 4.2

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Cl.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1

InChI

1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H

chave InChI

OPXKTCUYRHXSBK-UHFFFAOYSA-N

Informações sobre genes

human ... ADRB2(154)

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Aplicação

Clenbuterol hydrochloride has been used:
  • as an agonist for β-adrenergic receptor (β-AR) from chick skeletal muscle
  • to induce hypertrophic effects in masseter, digastric, and temporalis muscles of rat
  • as a reference β-agonist standard in tandem mass spectrometry(MS-MS)

Ações bioquímicas/fisiológicas

Clenbuterol hydrochloride is a β2-adrenoceptor agonist and bronchodilator. It is effective in improving peak expiratory flow rate (PEFR) in asthma patients. Clenbuterol is also a performance-enhancing drug as it stimulates the central nervous system and improves oxygen transport. Clenbuterol elicits cardio protective functionality in patients with dilated cardiomyopathy.

Aplicação

Nº do produto
Descrição
Preços

G004337

HPLC Analysis of Beta-Receptor Agonist Enantiomers on Astec® CHIROBIOTIC® T, application for HPLC

G004431

LC/MS Analysis of Clenbuterol In Plasma on Astec® CHIROBIOTIC® T with Phospholipid Removal using HybridSPE® Phospholipid, application for SPE, application for LC-MS

G004245

LC/MS Analysis of Clenbuterol Enantiomers in Plasma on Astec® CHIROBIOTIC® T after SPE using HybridSPE®-Phospholipid, application for HPLC

G004493

HPLC Analysis of Clenbuterol Enantiomers on Astec® CHIROBIOTIC® T, application for HPLC

G004596

HPLC Analysis of Clenbuterol Enantiomers on Astec® CHIROBIOTIC® T2, application for HPLC

G004621

HPLC Analysis of Clenbuterol Enantiomers on Astec® CHIROBIOTIC® V, application for HPLC

Pictogramas

Health hazard
GHS08

Palavra indicadora

Danger

Frases de perigo

H351,H360FD

Classificações de perigo

Carc. 2 - Repr. 1B

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
BCCB5150
BCBQ2163V
BCBQ1350V
BCBF1701V
BCBB8614V

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Supelco

C-081

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Terbutaline hemisulfate salt

Sigma-Aldrich

T2528

Terbutaline hemisulfate salt

C A Izeboud et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 48(9), 497-502 (1999-10-16)
To investigate the suppressive effects of the beta-agonist clenbuterol on the release of TNF-alpha and IL-6 in a lipopolysaccharide (LPS)-model of inflammation, both in vitro and in vivo. Human U-937 cell line (monocyte-derived macrophages), and male Wistar rats (200-250 g).
Jelka Pleadin et al.
Meat science, 86(3), 733-737 (2010-07-30)
The aim of this study was to determine the level of clenbuterol residues in muscle tissue of pigs after repeat administration in a growth-promoting dose. An anabolic dose of clenbuterol (20 μg/kg body mass per day) was administered orally to
I Semkova et al.
Brain research. Brain research reviews, 30(2), 176-188 (1999-10-19)
Neurotrophins and other neurotrophic factors have been shown to support the survival and differentiation of many neuronal populations of the central and peripheral nervous system. Therefore, administering neurotrophic factors could represent an alternative strategy for the treatment of acute and
Structural characterization of a new form of clenbuterol, a well-known decongestant and bronchodilator also used as a performance-enhancing drug
Toro R, et al.
Powder Diffraction, 28(2), 63-67 (2013)
A trial of clenbuterol in bronchial asthma.
Anderson G and Wilkins E
Thorax, 32(6), 717-719 (1977)
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