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C2105

Sigma-Aldrich

Z-Val-Ala-Asp fluoromethyl ketone

powder, ≥90% (TLC)

Sinônimo(s):

Z-VAD-FMK, Non-methylated

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About This Item

Fórmula empírica (Notação de Hill):
C21H28FN3O7
Número CAS:
161401-82-7
Peso molecular:
453.46
Número MDL:
MFCD03452883
Código UNSPSC:
12352209
ID de substância PubChem:
329774926
NACRES:
NA.77

Nível de qualidade

200

Ensaio

≥90% (TLC)

forma

powder

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF

InChI

1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1

chave InChI

SUUHZYLYARUNIA-YEWWUXTCSA-N

Amino Acid Sequence

Z-Val-Ala-Asp-OMe-FMK

Ações bioquímicas/fisiológicas

Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).

Características e benefícios

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Sigma-Aldrich

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Ac-YVAD-cmk ≥95% (HPLC)

Sigma-Aldrich

SML0429

Ac-YVAD-cmk

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