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B1125

Sigma-Aldrich

Bathocuproinedisulfonic acid disodium salt

7.2-9.1% purity dry basis (ICP), powder

Sinônimo(s):

2,9-Dimethyl-4,7-diphenyl-1,10-phenantrolinedisulfonic acid disodium salt, Disodium bathocuproinedisulfonate

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About This Item

Fórmula empírica (Notação de Hill):
C26H18N2Na2O6S2
Número CAS:
52698-84-7
Peso molecular:
564.54
Número MDL:
MFCD00011679
Código UNSPSC:
12171500
NACRES:
NA.47

Nome do produto

Bathocuproinedisulfonic acid disodium salt, for spectrophotometric det. of Cu, Fe

Ensaio

7.2-9.1% dry basis (ICP)

Formulário

powder

qualidade

for spectrophotometric det. of Cu, Fe

técnica(s)

titration: 90% using HCLO4 (Dry Basis)

cor

white to beige

solubilidade

H2O: 50 mg/mL

adequação

suitable for determination of copper

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

[Na+].[Na+].[S](=O)(=O)([O-])c1c(nc2c3nc(c(c(c3ccc2c1c5ccccc5)c4ccccc4)[S](=O)(=O)[O-])C)C

InChI

1S/C26H20N2O6S2.2Na/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2

chave InChI

RNGKZLRAVYPLJC-UHFFFAOYSA-L

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Descrição geral

Bathocuproinedisulfonic acid is a strong copper chelator. It is used for the determination of copper and iron in biological samples.

Aplicação

  • Bathocuproinedisulfonic acid disodium salt has been used as a copper chelator for specific assay in Arabidopsis seedlings.
  • It has been used as an electron chain-associated free radical production inhibitor for superoxide dismutase assay in cells.
  • It has been added to the culture media of trypanosomes as a copper chelator for the stabilization of cysteine.

Outras notas

Mixture of isomers

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
BCCG3838
BCCF6028
BCCD9450
BCCC8928
BCCC0310

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Minglin Lang et al.
Neurobiology of aging, 34(11), 2604-2612 (2013-07-06)
Disruption of copper homeostasis has been implicated in Alzheimer's disease (AD) during the last 2 decades; however, whether copper is a friend or a foe is controversial. Within a genetically tractable Drosophila AD model, we manipulated the expression of human
Jennifer Lowe et al.
The Journal of biological chemistry, 279(25), 25986-25994 (2004-04-14)
Ccc2p is homologous to the human Menkes and Wilson copper ATPases and is herein studied as a model for human copper transport. Most studies to date have sought to understand how mutations in the human Menkes or Wilson genes impair
Shinya Ogawa et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 909, 34-36 (2012-11-17)
HPLC eluent systems employing acetonitrile and methanol were evaluated for the quantitation of glutathione (GSH) and phytochelatin (PC(n)), a family of peptides implicated in heavy-metal detoxification in higher plants. The detection system is based on the dequenching of copper(I)-bathocuproine disulfonate
Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue.
Weydert CJ and Cullen JJ
Nature Protocols, 5, 51-66 (2010)
Shinya Ogawa et al.
Analytical chemistry, 81(21), 9199-9200 (2009-09-30)
Reoptimization of analytical conditions was performed for a high-performance liquid chromatographic (HPLC) detection system for Cu(I) chelators based on the dequenching of Cu(I)-bathocuproine disulfonate complexes that occurs in the presence of Cu(I) chelators. The revision corrects for emission and excitation
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