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M2172

Sigma-Aldrich

1-tioglicerol

BioXtra, ≥97%

Sinônimo(s):

αα-monotioglicerol, α1-tioglicerol, 3-Mercapto-1,2-propanodiol

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About This Item

Fórmula linear:
HSCH2CH(OH)CH2OH
Número CAS:
96-27-5
Peso molecular:
108.16
Beilstein:
1732046
Número CE:
202-495-0
Número MDL:
MFCD00004879
Código UNSPSC:
12352211
ID de substância PubChem:
24896709
NACRES:
NA.25

linha de produto

BioXtra

Nível de qualidade

200

Ensaio

≥97%

forma

liquid

Impurezas

≤0.0005% Phosphorus (P)

resíduo de ignição

≤0.1%

índice de refração

n20/D 1.527 (lit.)

pb

118 °C/5 mmHg (lit.)

densidade

1.25 g/mL at 25 °C (lit.)

traços de cátion

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

OCC(O)CS

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

chave InChI

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

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Descrição geral

1-Thioglycerol stimulates the synthesis of porphyrin in aerobically growing Escherichia coli. It is an inhibitor of glycerol kinase activity in vitro and in situ.

Aplicação

It has been used in a study to assess thiol-sensitive genes and promoters of Escherichia coli.

Nota de preparo

This product is miscible in ethanol (1 ml/ml, 50%, v/v), yielding a clear, colorless solution. It is also miscible in water (0.1 M).

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

210.2 °F - closed cup

Ponto de fulgor (°C)

99 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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W K Seltzer et al.
Life sciences, 39(16), 1417-1424 (1986-10-20)
The infantile form of glycerol kinase (GK) deficiency (McKusick No. 30703) (1) is characterized by adrenal cortical insufficiency, adrenal hypoplasia and developmental delay. The underlying biochemical mechanism(s) responsible for the observed clinical presentations are undetermined. Pursuant to our examination of
G T Javor
Journal of bacteriology, 171(10), 5607-5613 (1989-10-01)
The effect of 1-thioglycerol on the expression of genes of Escherichia coli was investigated. Pulse-labeled proteins from aerobically growing, 1-thioglycerol-treated E. coli were separated by two-dimensional gel electrophoresis, and their radioactivities were compared with those of identical proteins from nontreated
G T Javor et al.
Journal of bacteriology, 170(7), 3291-3293 (1988-07-01)
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive
P Tengvall et al.
Biomaterials, 17(10), 1001-1007 (1996-05-01)
Thiol-modified surfaces are chemically well defined and suited for surface biological model experiments and biomaterials research. 3-Mercapto-1,2-propanediol (mercaptoglycerol, MG), immobilized on gold, spontaneously binds immunoglobulins from human serum and activates the complement system. The surface-bound complement factors were detected by
Jonas Wetterö et al.
Biomaterials, 23(4), 981-991 (2002-01-17)
Since the realization of a complement activation capacity by artificial surfaces upon contact with blood, a common belief has evolved that charged nucleophilic surface groups such as amine (-NH2) and hydroxyl (-OH) react with and eventually bind to the internal
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