AV32623

Anti-HIC1 antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-Hypermethylated in cancer 1
• Código UNSPSC: 12352203
• NACRES: NA.43
• clone: polyclonal
• application: WB
• reatividade de espécies: human
• técnica(s): western blot: suitable
• citations: 1

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: 74 kDa
• reatividade de espécies: human
• concentração: 0.5 mg - 1 mg/mL
• técnica(s): western blot: suitable
• nº de adesão NCBI: NP_001091672
• nº de adesão UniProt: Q14526-2
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... HIC1(3090)

Descrição

Descrição geral

HIC1 is a tumor suppressor that interacts with SIRT1 to regulate p53-depenedent responses to DNA damage.
Rabbit Anti-HIC1 antibody recognizes human, mouse, and rat HIC1.

Imunogênio

Synthetic peptide directed towards the N terminal region of human HIC1

Aplicação

Rabbit Anti-HIC1 antibody can be used for western blot applications at a concentration of 0.25μg/ml.

Ações bioquímicas/fisiológicas

HIon Channel1 is a transcriptional repressor. HIon Channel1 may act as a tumor suppressor. HIon Channel1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIon Channel1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.

Sequência

Synthetic peptide located within the following region: ALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPA

forma física

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable