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A4979

Sigma-Aldrich

Anti-Water Channel Aquaporin 5 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Sinônimo(s):

Anti-AQP-5, Anti-PPKB

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41
conjugado:
unconjugated
application:
WB
clone:
polyclonal
reatividade de espécies:
mouse, rat
citations:
7
técnica(s):
western blot: 1:200-1:500 using mouse salivary gland and rat lung

fonte biológica

rabbit

Nível de qualidade

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

lyophilized powder

reatividade de espécies

mouse, rat

técnica(s)

western blot: 1:200-1:500 using mouse salivary gland and rat lung

nº de adesão UniProt

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

mouse ... Aqp5(11830)
rat ... Aqp5(25241)

Descrição geral

Anti-Water Channel Aquaporin 5 binds to aquaporin 5 from mouse salivary gland and rat lung membranes.
Aquaporin-5 is part of a family of aquaporins that function to transport water across cell membranes. AQP5 is involved in tear, saliva, and sweat production.
Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0).

Imunogênio

peptide corresponding to residues 251-265 of rat AQP5. The sequence is identical in mouse and 10/16 residues identical in human.

Aplicação

Rabbit Anti-Water Channel Aquaporin 5 antibody can be used for western blot at a dilution of 1:200-1:500 using mouse salivary gland and rat lung tissue extracts.

forma física

Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA, ≤0.1% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Christian Müller et al.
The Journal of experimental biology, 209(Pt 20), 4067-4076 (2006-10-07)
Using primers against highly conserved regions of mammalian and bird aquaporins in RT-PCR experiments, we amplified products derived from duck (Anas platyrhynchos) nasal gland RNA that were identified as homologues of mammalian and chicken aquaporin 1 and aquaporin 5 cDNAs
A S Verkman et al.
American journal of physiology. Renal physiology, 278(1), F13-F28 (2000-02-08)
The aquaporins (AQPs) are a family of small membrane-spanning proteins (monomer size approximately 30 kDa) that are expressed at plasma membranes in many cells types involved in fluid transport. This review is focused on the molecular structure and function of
J W Snuggs et al.
Scientific reports, 11(1), 3164-3164 (2021-02-06)
The central region of the intervertebral disc (IVD) is rich in proteoglycans, leading to a hyperosmotic environment, which fluctuates with daily loading. The cells of the nucleus pulposus (NP cells) have adapted to this environment via the function of tonicity
Michael G Haase et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 62(5), 355-368 (2014-03-29)
Ionizing radiation (IR) leads to fibrosing alveolitis (FA) after a lag period of several weeks to months. In a rat model, FA starts at 8 weeks after IR. Before that, at 5.5 weeks after IR, the transcription factors Sp1 (stimulating
Peter Agre et al.
The Journal of physiology, 542(Pt 1), 3-16 (2002-07-04)
The water permeability of biological membranes has been a longstanding problem in physiology, but the proteins responsible for this remained unknown until discovery of the aquaporin 1 (AQP1) water channel protein. AQP1 is selectively permeated by water driven by osmotic

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