AB15858
Anti-Aquaporin 5 Antibody
1 mg/mL, Chemicon®
Sinônimo(s):
AQP5
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
purificado por
affinity chromatography
reatividade de espécies
mouse, rat
fabricante/nome comercial
Chemicon®
concentração
1 mg/mL
técnica(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
mouse ... Aqp5(11830)
rat ... Aqp5(25241)
Descrição geral
Aquaporins (AQPs) are a family of channel proteins that allow water or very small solutes to pass, functioning in tissues where the rapid and regulated transport of fluid is necessary, such as the kidney, lung, and salivary glands. Aquaporin 5 is considered to play an important role in water movement across the plasma membrane in salivary fluid secretion and corneal/lens lubrication and is a focus of studies illucidating bechanisms underlying diabetic xerostomia.
Especificidade
Aquaporin 5 (AQP5). By Western blot the antibody reacts with a band at ~ 24 kDa on rat submaxillary gland lysate.
Imunogênio
Epitope: Cytoplasmic domain
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of rat Aquaporin 5.
Aplicação
Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected Aquaporin 5 in rat lung and mouse trachea tissue.
Immunohistochemistry Analysis: A representative lot from independent laboratories detected Aquaporin 5 in various paraformaldehyde fixed tissues (see references).
Immunohistochemistry Analysis: A representative lot from independent laboratories detected Aquaporin 5 in various paraformaldehyde fixed tissues (see references).
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Signaling
Developmental Signaling
This Anti-Aquaporin 5 (AQP5) Antibody is validated for use in WB for the detection of Aquaporin 5 (AQP5).
Qualidade
Evaluated by Western Blotting in rat salivary gland tissue lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected Aquaporin 5 in 10 µg of rat salivary gland tissue lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected Aquaporin 5 in 10 µg of rat salivary gland tissue lysate.
Descrição-alvo
~28 kDa observed
forma física
ImmunoAffinity Purified
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
Armazenamento e estabilidade
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
Nota de análise
Control
Tested on Rat Salivary Gland Lysate
Tested on Rat Salivary Gland Lysate
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
S Raina et al.
The Journal of biological chemistry, 270(4), 1908-1912 (1995-01-27)
The Aquaporin family of water channels plays a fundamental role in transmembrane water movements in numerous plant and animal tissues. Since the molecular pathway by which water is secreted by salivary glands is unknown, a cDNA was isolated from rat
Verification and spatial localization of aquaporin-5 in the ocular lens.
Grey, AC; Walker, KL; Petrova, RS; Han, J; Wilmarth, PA; David, LL; Donaldson, PJ; Schey, KL
Experimental Eye Research null
Wenli Yang et al.
PloS one, 9(11), e113451-e113451 (2014-11-25)
The hepatopulmonary syndrome (HPS) develops when pulmonary vasodilatation leads to abnormal gas exchange. However, in human HPS, restrictive ventilatory defects are also observed supporting that the alveolar epithelial compartment may also be affected. Alveolar type II epithelial cells (AT2) play
S M Kreda et al.
American journal of respiratory cell and molecular biology, 24(3), 224-234 (2001-03-14)
Aquaporins (AQPs) facilitate water transport across epithelia and play an important role in normal physiology and disease in the human airways. We used in situ hybridization and immunofluorescence to determine the expression and cellular localization of AQPs 5, 4, and
Yao Chen et al.
Respiratory research, 13, 1-1 (2012-01-05)
Distal alveolar morphogenesis is marked by differentiation of alveolar type (AT)-II to AT-I cells that give rise to the primary site of gas exchange, the alveolar/vascular interface. Endothelial-Monocyte Activating Polypeptide (EMAP) II, an endogenous protein with anti-angiogenic properties, profoundly disrupts
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