A4685

Luminol sodium salt

luminescent, ≥98% (titration), powder and chunks

• Sinônimo(s): 3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione
• Fórmula linear: C₈H₆N₃O₂Na
• Número CAS: 20666-12-0
• Peso molecular: 199.14
• Número MDL: MFCD00161491
• Código UNSPSC: 12352204
• ID de substância PubChem: 24890898
• NACRES: NA.83

Propriedades

• Nome do produto: Luminol sodium salt,
• Ensaio: ≥98% (titration)
• Nível de qualidade: 300
• Formulário: powder and chunks
• solubilidade: water: 50 mg/mL, clear to very slightly hazy, colorless to faint red
• cadeia de caracteres SMILES: O=C1NN([Na])C(C2=CC=CC(N)=C21)=O
• InChI: 1S/C8H7N3O2.Na/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12;/h1-3H,(H4,9,10,11,12,13);/q;+1/p-1
• chave InChI: RVJVDCVIJCBUTH-UHFFFAOYSA-M

Descrição

Aplicação

Luminol sodium salt has been used:

• as a component of MEBSS buffer in a bioluminescence assay to detect peroxidase activity in whole blood samples
• to study protein interaction in whole-cell lysates by immunoprecipitation
• for in vitro reactive oxygen species (ROS) quantification in CD45⁺ and CD45− cells

Ações bioquímicas/fisiológicas

Luminol is a redox-sensitive chemiluminescent compound. It emits blue luminescence when the basic aqueous solution of luminol having oxygen atoms come in contact with oxidizing agents like potassium ferricyanide. It is highly stable and is applicable in various fields such as analytical chemistry, metallurgy, biochemistry, and forensics for detecting reactive species. Luminol has the potential to detect defects in neutrophils ex vivo during oxidative metabolism defects such as chronic granulomatous disease and myeloperoxidase deficiency.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves