A2661
Acetylcholine chloride
suitable for cell culture
Sinônimo(s):
ACh
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About This Item
Fórmula linear:
(CH3)3N+CH2CH2OCOCH3Cl-
Número CAS:
Peso molecular:
181.66
Beilstein:
3571875
Número CE:
Número MDL:
Código UNSPSC:
12352209
eCl@ss:
32190102
ID de substância PubChem:
NACRES:
NA.75
Produtos recomendados
fonte biológica
synthetic
Nível de qualidade
Ensaio
~99%
Formulário
powder
técnica(s)
cell culture | mammalian: suitable
pf
146-150 °C (lit.)
solubilidade
water: 100 mg/mL, clear, colorless
Condições de expedição
ambient
temperatura de armazenamento
room temp
cadeia de caracteres SMILES
[Cl-].CC(=O)OCC[N+](C)(C)C
InChI
1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
chave InChI
JUGOREOARAHOCO-UHFFFAOYSA-M
Informações sobre genes
human ... CHRM3(1131)
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Aplicação
Acetylcholine chloride has been used in the preparation of acetylcholine, that is used as a common vehicle for iontophoresis of acetylcholine (ACh). It has also been used to treat aNS-1 derived neurons for cAMP (cyclic adenosine monophosphate) assay and also used to check their ability to influence G protein-coupled receptors (GPCRs).
Ações bioquímicas/fisiológicas
Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.
Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Gloves
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The habenulo-interpeduncular pathway, a highly conserved cholinergic system, has emerged as a valuable model to study left-right asymmetry in the brain. In larval zebrafish, the bilaterally paired dorsal habenular nuclei (dHb) exhibit prominent left-right differences in their organization, gene expression
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